Results 81 to 90 of about 9,257 (204)
Arthritis &Rheumatology, Volume 78, Issue 8, Page 1692-1699, August 2026.Objective Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE) and is partially driven by type I interferon signaling. Anifrolumab, an approved treatment for patients with SLE, has been investigated in a phase 2 trial in patients with LN receiving standard therapy (TULIP‐LN, ClinicalTrials.gov identifier ...
Andrea Fava +8 more
wiley +1 more source
Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of
Xinxin Xu +10 more
wiley +1 more source
Osteoarthritis: Epidemiology, Diagnosis, and Treatment
MedComm, Volume 7, Issue 7, July 2026.Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru +7 more
wiley +1 more source
The role of visfatin in prostate cancer [PDF]
The aim of this study was to investigate the role of the adipokine visfatin as a possible molecular mediator between obesity and prostate cancer. Visfatin, an adipokine that is elevated in obesity and has many proposed roles and has been linked to a ...
Patel, Snehal T.
core
Expression of Visfatin in the lenti-null group and lenti-visfatin group.
, 2016 A, Western blot analysis was used to detect the visfatin expression in the represent samples of carotid plaques from the lenti-null group and lenti-visfatin group respectively after lentivirus transduction for 3 days, 7 days and 4 weeks. B, Real-time PCR
Tianjun Qi (2156758) +13 more
core +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease closely associated with obesity. Adipokines secreted by adipose tissue play critical roles in disease progression. This study focuses on the adipokine leptin and investigates its relationship with knee osteoarthritis.
Ruifu Li +5 more
wiley +1 more source
The Role of Visfatin/NAMPT in the Pathogenesis of Psoriasis
MetabolitesIntrodcution: Psoriasis is a complex, chronic, immunologically, inflammatory, and environmentally mediated disease which may affect not only the skin, but also nails, and joints. This dermatosis is known for hyperproliferation, parakeratosis, dysregulated differentiation of keratinocytes, lack of granular layer of the skin and impaired apoptosis of ...
Mateusz Matwiejuk +7 more
openaire +3 more sources
Obesity Reviews, Volume 27, Issue 7, July 2026.ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso +7 more
wiley +1 more source
Visfatin Levels and Cardiovascular Parameters among Children and Adolescents with Type 1 Diabetes Mellitus [PDF]
Zagazig University Medical JournalBackground: The risk of cardiovascular problems such as heart failure is higher in those with type 1 diabetes mellitus (T1DM). In cardiovascular-metabolic illnesses, potential diagnostic applications for the novel adipokine visfatin have been discovered.
ghada abdellatif +6 more
doaj +1 more source
Experimental Physiology, Volume 111, Issue 7, Page 3203-3215, 1 July 2026.Abstract We investigated whether higher body mass index (BMI) modifies time‐resolved maternal autonomic control and maternal cardio‐electrohysterographic coupling (MCEC) during the first stage of labour. Seventy‐nine women were studied and, for the present analysis, grouped as Control (C; n = 41) and high BMI (HBMI; n = 38).
Carlos Gabriel Varela‐Albarrán +6 more
wiley +1 more source