Results 111 to 120 of about 399,468 (278)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The Usage of ANN for Regression Analysis in Visible Light Positioning Systems. [PDF]

open access: yesSensors (Basel), 2022
Chaudhary N   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Indoor Visible Light Fingerprint Location Method Based on Marine Predator Algorithm-Optimized Least Squares Support Vector Machine

open access: yesApplied Sciences
To increase the accuracy of indoor visible light positioning, a novel indoor visible light localization technique based on the marine predator algorithm-optimized least squares support vector machine (MPA-LSSVM) is suggested.
Yuanjia Mei, Yong Deng
doaj   +1 more source

Self-Sufficient Sensor Node Embedding 2D Visible Light Positioning through a Solar Cell Module. [PDF]

open access: yesSensors (Basel), 2022
Cappelli I   +5 more
europepmc   +1 more source

A Visible Light Based Indoor Positioning System

open access: yes, 2015
In this paper, we propose a novel indoor localization scheme that exploits ubiquitous visible lights, which are necessarily and densely deployed in almost all indoor environments. We unveil two phenomena of lights available for positioning: 1) the light strength varies according to different light sources, which can be easily detected by light sensors ...
Hu, Yiqing   +7 more
openaire   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Calibration of Visible Light Positioning Systems with a Mobile Robot. [PDF]

open access: yesSensors (Basel), 2021
Amsters R   +3 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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