Results 71 to 80 of about 1,394,895 (334)

Singularities in gravitational collapse with radial pressure [PDF]

, 2001
We analyze spherical dust collapse with non-vanishing radial pressure, $\Pi$, and vanishing tangential stresses. Considering a barotropic equation of state, $\Pi=\gamma\rho$, we obtain an analytical solution in closed form---which is exact for $\gamma=-1,
A. Ori, B. J. Carr, C. J. S. Clarke, C. J. S. Clarke, C. W. Misner, D. Christodoulou, D. Kramer, D. M. Eardley, F. I. Cooperstock, F. J. Tipler, F. J. Tipler, G. Darmois, G. Lemaître, G. Magli, I. H. Dwivedi, J. C. Miller, J. F. V. Rocha, M. A. Podurets, P. S. Joshi, P. S. Joshi, R. Geroch, R. i. Penrose, R. Penrose, R. Penrose, S. Jhingan, S. Jhingan, S. S. Deshingkar, S. W. Hawkins, Sanjay Jhingan, Sérgio M. C. V. Gonçalves, T Harada, T. Harada, T. Nakamura   +32 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A Novel Structure for Double Negative NIMs towards UV Spectrum with High FOM

, 2010
A novel ring structure is proposed for double negative NIMs at visible light spectrum with high FOM (e.g. about 11 at a wavelength of 583 nm) and low loss.
Chen, Chen, Chettiar, Chettiar, Dolling, Dolling, Dolling, Jianwei Tang, Johnson, Linden, Penciu, Pendry, Sailing He, Shelby, Smith, Soukoulis, Veselago, Xiao, Yao, Yen, Zhang, Zhang, Zhou   +22 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

NLTE solar irradiance modeling with the COSI code

, 2010
Context. The solar irradiance is known to change on time scales of minutes to decades, and it is suspected that its substantial fluctua- tions are partially responsible for climate variations. Aims.
A. I. Shapiro, Asplund, Auer, Auer, Avrett, Bruls, Busá, Collet, Domingo, E. Rozanov, Fontenla, Fontenla, Foukal, Fröhlich, Gray, Haberreiter, Hamann, Harder, Hubeny, Irwin, Knowles, Krivova, Krivova, Krivova, Krupp, Kupka, Kupka, Kurucz, Kurucz, Lambert, Lean, M. Haberreiter, M. Schoell, McClintock, Penza, Penza, Rossi, Rottman, Rybicki, Rybicki, Sauval, Scharmer, Scharmer, Schmutz, Seaton, Short, Tatum, Tsuji, Uitenbroek, Vernazza, Vitas, W. Schmutz, Wallace, Willson   +53 more
core   +1 more source

Collision strengths and transition probabilities for Co III forbidden lines [PDF]

, 2016
In this paper we compute the collision strengths and their thermally-averaged Maxwellian values for electron transitions between the fifteen lowest levels of doubly-ionised cobalt, Co^{2+}, which give rise to forbidden emission lines in the visible and ...
Sochi, Taha, Storey, P. J.
core   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Use of Indices in RGB and Random Forest Regression to Measure the Leaf Area Index in Maize

Agronomy
In the cultivation of maize, the leaf area index (LAI) serves as an important metric to determine the development of the plant. Unmanned aerial vehicles (UAVs) that capture RGB images, along with random forest regression (RFR), can be used to indirectly ...
Leonardo Pinto de Magalhães, Fabrício Rossi   +1 more
doaj   +1 more source

Is the Pale Blue Dot unique? Optimized photometric bands for identifying Earth-like exoplanets

, 2016
The next generation of ground and space-based telescopes will image habitable planets around nearby stars. A growing literature describes how to characterize such planets with spectroscopy, but less consideration has been given to the usefulness of ...
Arney, Giada, Catling, David C., Charnay, Benjamin, Krissansen-Totton, Joshua, Meadows, Victoria, Robinson, Tyler D., Schwieterman, Edward W.   +6 more
core   +1 more source