Results 1 to 10 of about 155,041 (248)

Characterization of retinal function and structure in the MPTP murine model of Parkinson’s disease

open access: yesScientific Reports, 2022
In addition to well characterized motor symptoms, visual disturbances are increasingly recognized as an early manifestation in Parkinson’s disease (PD). A better understanding of the mechanisms underlying these changes would facilitate the development of
Katie K. N. Tran   +7 more
doaj   +1 more source

Development and characterization of DNA aptamer against Retinoblastoma by Cell-SELEX

open access: yesScientific Reports, 2022
Retinoblastoma (RB) is the most common paediatric intraocular tumour. The management of RB has improved the survival and vision with recent advances in the treatment.
Bhavani Shankar Maradani   +2 more
doaj   +1 more source

In vitro assessment of the biocompatibility of chemically treated silicone materials with human lens epithelial cells

open access: yesScientific Reports, 2022
Cytotoxicity testing is a regulatory requirement for safety testing of new ocular implants. In vitro toxicity tests determine whether toxic chemicals are present on a material surface or leach out of the material matrix.
Elizabeth C. Y. Kao   +4 more
doaj   +1 more source

Laser in situ keratomileusis versus Artisan lens implantation in correcting ametropia after penetrating keratoplasty for keratoconus

open access: yesBMC Ophthalmology, 2023
Purpose To compare the long-term safety and efficacy of laser in situ keratomileusis (LASIK) with Artisan phakic intraocular lens implantation to correct refractive errors after penetrating keratoplasty (PK) for keratoconus.
Sepehr Feizi   +3 more
doaj   +1 more source

A Rapid Screening Platform for Simultaneous Evaluation of Biodegradation and Therapeutic Release of an Ocular Hydrogel

open access: yesPharmaceutics, 2023
This study attempts to address the challenge of accurately measuring the degradation of biodegradable hydrogels, which are frequently employed in drug delivery for controlled and sustained release.
Brandon Ho   +4 more
doaj   +1 more source

Laboratory analysis and ray visualization of diffractive optics with enhanced intermediate vision

open access: yesBMC Ophthalmology, 2021
Background To assess the optical behavior of a new diffractive intraocular lens (IOL) and compare its performance to that of an established extended-depth-of-focus (EDOF) IOL.
Hyeck-Soo Son   +4 more
doaj   +1 more source

An In-Silico Study on the Most Effective Growth Factors in Retinal Regeneration Utilizing Tissue Engineering Concepts

open access: yesJournal of Ophthalmic & Vision Research, 2021
Purpose: Considering the significance of retinal disorders and the growing need to employ tissue engineering in this field, in-silico studies can be used to establish a cost-effective method.
Nima Beheshtizadeh   +3 more
doaj   +1 more source

Development of an In Vitro Blink Model for Ophthalmic Drug Delivery

open access: yesPharmaceutics, 2021
Purpose: The purpose of this study was to develop an advanced in vitro blink model that can be used to examine the release of a wide variety of components (for example, topical ophthalmic drugs, comfort-inducing agents) from soft contact lenses. Methods:
Chau-Minh Phan   +5 more
doaj   +1 more source

Visualization of Forward Light Scatter in Opacified Intraocular Lenses and Straylight Assessment

open access: yesDiagnostics, 2021
Background: Qualitative visualization of forward light scatter and quantitative straylight measurement of intraocular lenses (IOLs). Methods: We analyzed two calcified IOL-explants, the Euromaxx ALI313Y (Argonoptics GmbH) and the LS-312 MF30 (Oculentis ...
Hyeck-Soo Son   +6 more
doaj   +1 more source

In-vitro glistening formation in six different foldable hydrophobic intraocular lenses

open access: yesBMC Ophthalmology, 2021
Background Glistenings describe small, refractile microvacuoles that may arise within the intraocular lens (IOL) material and reduce the patients’ quality of vision.
Tamer Tandogan   +5 more
doaj   +1 more source

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