Results 141 to 150 of about 5,401 (177)

Real-world management and long-term outcomes in adolescent, young adult, and adult medulloblastoma: Experience from a monocentric series with multimodal and targeted approaches. [PDF]

open access: yesNeurooncol Pract
Bosio A   +18 more
europepmc   +1 more source

A rare case of metastatic super giant basal cell carcinoma of the thoracoabdominal wall. [PDF]

open access: yesJAAD Case Rep
Lee DE   +4 more
europepmc   +1 more source

Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors. [PDF]

open access: yesInt J Mol Sci
Papaccio F   +9 more
europepmc   +1 more source

Vismodegib

Annals of Pharmacotherapy, 2014
Vismodegib (GDC-0449, Erivedge®) is a novel small molecule antagonist of the hedgehog (Hh) pathway that binds to smoothened (SMO) and leads to inhibition of an aberrant activation of the Hh pathway. Dysregulated Hh signaling results in uncontrolled proliferation in basal cell carcinoma (BCC) and has also been found present in medulloblastoma, and many ...
Lisa A Thompson
exaly   +5 more sources

Vismodegib

open access: yesReactions Weekly, 2017
By definition, a drug is a medicine or substance that exerts a physiologic effect on an organism. In dermatology, medications and substances are utilized on a daily basis from topical treatments to anesthetics in surgery.
Siddiqui, Fariha   +3 more
core   +5 more sources

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