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Pathogenesis of maedi-visna

Veterinary Record, 1987
In most cases, maedi-visna virus infection is characterised by a subclinical, persistent virus-carrier state. However, in heavily infected flocks, economically significant disease does occur, mainly apparent as ill-thrift and chronic respiratory disease (maedi) in older ewes and as an indurative mastitis, which can result in delayed weight gain of ...
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Maedi/visna: a review

Veterinary Record, 1980
A brief history of the occurrence of maedi/visna or maedi/visna related diseases is given. The clinical features and diagnosis are described. Recent experimental work performed in an attempt to resolve the pathogenetic features of slowness and persistence of infection, characteristic of maedi/visna, is covered.
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Characterization of visna virus mRNA

Journal of Virology, 1979
Visna virus is a retrovirus responsible for a classical slow infection of the central nervous system of sheep. In the present work we focused our attention on the viral mRNA's. We found that, during the acute infection in vitro, (i) viral mRNA's amount to only 0.1% of the total cytoplasmic RNA, (ii) 20% of the total cytoplasmic viral RNA is found in ...
P, Filippi   +3 more
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Pathogenesis of Visna

1987
Visna, the prototype of slow infections (Sigurdsson, 1954), is a menin-goencephalitis of sheep, caused by a retrovirus (Petursson et al., 1979) which belongs to the group of lentiviruses and is related to the recently isolated human virus that causes AIDS (Sonigo et al., 1985).
G. Georgsson   +2 more
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Infectivity of visna virus DNA

Virology, 1976
Abstract Deoxyribonucleic acid isolated from cells infected with the RNA containing slow virus visna confers on uninfected cells the capacity to synthesize new virus. The cytopathic agent isolated in these experiments has the biological and biochemical properties of visna virus, and the active material is DNA by several criteria, the most important ...
A T, Haase   +3 more
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Visna bei der Ziege

Zentralblatt für Veterinärmedizin Reihe B, 2010
Zusammenfassung Es wurden 19 Ziegen untersucht, die aus einer Herde stamniten, in der die fur Visna des Schafes typischen zentralnervosen Storungen und pathologischhistologischen Veranderungen vorkamen. Bei der klinischen Untersuchung hatten die Ziegen Visna-Symptome wie zentralnervosbedingte Storungen mit Paresen und Paralysen, in der Nachhand ...
E. Weingold, B. Triemer
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Visna in Sheep

1979
In 1935 the first cases of a previously unknown paralytic disease were seen in older age-groups of sheep in a south-western region of Iceland (Fig l). From 1935-1952 cases were increasing causing considerable loss of sheep in the affected flocks (l, 2, 3).
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Visna Virus Genome

1990
Visna virus was originally recognized in the 1930s as the etiologic agent of an unusual and sporadic outbreak of a transmissible neurologic disease that simultaneously appeared with several chronic pneumonic diseases affecting sheep in Iceland (Sigurdsson, 1954, 1957; Sigurdsson and Palsson, 1958). Visna means “wasting” in Icelandic and became the name
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Experimental visna in foetal Icelandic sheep

Journal of Comparative Pathology, 1978
Abstract Visna is a chronic neurological disease of sheep caused by a slow infection with a naturally occurring ovine retrovirus. The present study was focused on the influence of age on the pathogenesis of this infection and involved intrauterine inoculation of 7 sheep foetuses at about 90 days of gestation with slaughter at birth, 6 to 7 weeks ...
G, Georgsson   +4 more
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