Results 51 to 60 of about 340,097 (306)

Integrated results from the COPERNICUS and GALILEO studies. [PDF]

open access: yes, 2017
OBJECTIVES: To report on the efficacy and safety of intravitreal aflibercept in patients with macular edema secondary to central retinal vein occlusion (CRVO) in an integrated analysis of COPERNICUS and GALILEO.
Ahlers, Christiane   +13 more
core   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Prognostic Factors for Postoperative Visual Acuity in Patients with Rhinogenic Optic Neuropathy

open access: yesJournal of Ophthalmology, 2019
Purpose. To examine the prognostic factors related to postoperative visual acuity in patients with rhinogenic optic neuropathy. Study Design. Retrospective observational study. Materials and Methods.
Mitsuya Otsuka   +6 more
doaj   +1 more source

Screening for significant refractive error using a combination of distance visual acuity and near visual acuity. [PDF]

open access: yesPLoS ONE, 2015
To explore the effectiveness of using a series of tests combining near visual acuity (NVA) and distance visual acuity (DVA) for large-scale screenings for significant refractive error (SRE) in primary school children.Each participant underwent DVA, NVA ...
Peiyao Jin   +6 more
doaj   +1 more source

Initial Findings on Visual Acuity Thresholds in an African Elephant (\u3cem\u3eLoxodonta africana\u3c/em\u3e) [PDF]

open access: yes, 2010
There are only a few published examinations of elephant visual acuity. All involved Asian elephants (Elephas maximus) and found visual acuity to be between 8′ and 11′ of arc for a stimulus near the tip of the trunk, equivalent to a 0.50 cm gap, at a ...
Dale, Robert H.I.   +4 more
core   +1 more source

Visual acuity in larval zebrafish: behavior and histology [PDF]

open access: yes, 2010
BACKGROUND: Visual acuity, the ability of the visual system to distinguish two separate objects at a given angular distance, is influenced by the optical and neuronal properties of the visual system.
Biehlmaier, O   +3 more
core   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

open access: yesMolecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat   +18 more
wiley   +1 more source

Heterophoria: Vergence stability and visual acuity after asymmetric saccades [PDF]

open access: yes, 2012
Many patients with heterophoria report on symptoms related to impaired vision. To investigate whether these symptoms are provoked by saccades this study examines whether in heterophoria effects on intrasaccadic and postsaccadic vergence movements are ...
Bickmann, Alexander   +5 more
core   +2 more sources

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

open access: yesFEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma   +10 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy