Results 71 to 80 of about 4,780,000 (294)

Trends and Techniques in Visual Gaze Analysis [PDF]

, 2009
Visualizing gaze data is an effective way for the quick interpretation of eye tracking results. This paper presents a study investigation benefits and limitations of visual gaze analysis among eye tracking professionals and researchers.
Dachselt, Raimund, Lindley, Craig A., Nacke, Lennart E., Stellmach, Sophie   +3 more
core   +2 more sources

Prevalence and spatial concordance of visual field deterioration in fellow eyes of glaucoma patients. [PDF]

, 2014
PurposeTo examine the prevalence of visual field deterioration in contralateral eyes of patients with worsening open-angle glaucoma and to evaluate the spatial concordance of visual field deterioration between both eyes.MethodsOne hundred sixteen open ...
Caprioli, Joseph, Kim, Min Kyo, Lee, Jun Mo, Morales, Esteban   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Scleral remodeling in early adulthood: the role of FGF-2

Scientific Reports, 2023
Emmetropization, a natural process of ocular elongation, is closely associated with scleral remodeling. The Fibroblast growth factor-2 (FGF-2) was reported involved in scleral remodeling in myopia models.
Yingyan Qin, Taixiang Liu, Zhaotian Zhang, Shuwen Xing, Li Gong, Yao Ni   +5 more
doaj   +1 more source

Coordinated optimization of visual cortical maps (I) Symmetry-based analysis [PDF]

, 2012
In the primary visual cortex of primates and carnivores, functional architecture can be characterized by maps of various stimulus features such as orientation preference (OP), ocular dominance (OD), and spatial frequency.
A Cimponeriu, A Das, A Grinwald, A Shmuel, A Shmuel, A Soward, AA Koulakov, AA Koulakov, B Chapman, B Chapman, BJ Farley, CF Stevens, CJ Shatz, CJ Shatz, DB Chklovskii, DH Hubel, DL Adams, Dominik Heide, E Bartfeld, E Bodenschatz, E Erwin, E Erwin, F Wolf, F Wolf, F Wolf, FH Busse, Fred Wolf, GG Blasdel, GG Blasdel, GG Blasdel, GJ Goodhill, GJ Goodhill, GJ Mitchison, H Nakagama, H Yu, HY Lee, JA Bednar, JB Swift, JC Horton, JC Horton, Justin C. Crowley, K Obermayer, K Obermayer, K Obermayer, K Obermayer, K Ohki, K Ohki, KD Miller, L Reichl, L Reichl, Lars Reichl, LE White, LE White, M Hubener, M Kaschube, M Kaschube, M Kaschube, M Kaschube, M Schnabel, M Weliky, MA Carreira-Perpinan, MA Carreira-Perpinan, MA Carreira-Perpinan, Matthias Kaschube, MC Crair, MC Crair, MC Cross, MW Cho, MW Cho, N Mayer, ND Mermin, NP Issa, NP Issa, NV Swindale, NV Swindale, NV Swindale, NV Swindale, NV Swindale, NV Swindale, NV Swindale, NV Swindale, NV Swindale, Olaf Sporns, PC Bressloff, PC Bressloff, PC Bressloff, PJ Thomas, R Durbin, R Engelmann, RAW Galuske, S Grossberg, S LeVay, S Löwel, S Löwel, SC Rao, Siegrid Löwel, T Bonhoeffer, T Bonhoeffer, T Bonhoeffer, V Braitenberg, W Zhang, WH Bosking, X Xu, Y Li, Y Matsuda   +104 more
core   +4 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Quantitative PA tomography of high resolution 3-D images: Experimental validation in a tissue phantom

Photoacoustics, 2020
Quantitative photoacoustic tomography aims to recover the spatial distribution of absolute chromophore concentrations and their ratios from deep tissue, high-resolution images.
Jens Buchmann, Bernhard Kaplan, Samuel Powell, Steffen Prohaska, Jan Laufer   +4 more
doaj   +1 more source