Results 41 to 50 of about 736 (237)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Detecting New Visual Binaries in Gaia DR3 with Gaia and Two Micron All Sky Survey (2MASS) Photometry. II. Speckle Observations of 16 Low-separation Systems

The Astronomical Journal
Here we present speckle observations of 16 low-separation ( s < 30 au) high-probability candidate binaries from the catalog by Medan et al., where secondaries typically lack astrometric solutions in Gaia. From these speckle observations, we find a second
Ilija Medan, Sébastien Lépine, Zachary Hartman, Keivan G. Stassun   +3 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Orbits of Six Triple Systems

The Astronomical Journal
Joint analysis of position measurements and radial velocities of six triple stellar systems is conducted to determine their inner and/or outer orbits. Accumulation of such data is needed to study the architecture of stellar hierarchies and its relation ...
Andrei Tokovinin
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Precise Physical Parameters, Habitability, and Orbital Stability of Sun-like SB2 Systems: HD 130669, HD 184467, HD 191854, and HD 214222

The Astronomical Journal
This work analyzes four Sun-like double-lined spectroscopic binary systems by combining visual and spectroscopic observational data with Al-Wardat’s atmospheric modeling method to accurately determine their fundamental parameters.
Ahmad Abushattal, Nikolaos Georgakarakos, Mashhoor A. Al-Wardat, Bilal Algnamat, Hassan B. Haboubi, Deshinta Arrova Dewi, Enas M. Abu-Alrob, Abdallah M. Hussein   +7 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Processing of Simulated and Experimental Images of Closely Spaced Binary Stars Using Speckle Interferometry

, 2016
Theory and methods of processing speckle interferometry data from close visual binary stars are presented and implemented. The effects of the optical systems used for observing close visual binary stars are explained and simulated from both the ...
Smidth, Niels
core   +1 more source

Classical Observations of Visual Binary and Multiple Stars [PDF]

Proceedings of the International Astronomical Union, 2006
AbstractChanges in the double star database are highlighted, describing various methods of observation (both historically and those of the past few years) and their effectiveness in different regimes of separation space. The various niches for wide- and narrow-field work as they apply to double and multiple stars are examined and the different types of
openaire   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source