Results 171 to 180 of about 2,319,781 (255)

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

Advanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg, Anastasia Lopatina, Hao Ruan, Tom Scheidt, Simone Mosna, Emre Pekbilir, Julia Bieber, Frank Schäfer‐Depoix, Katharina Landfester, Carla Schmidt, Martin M. Möckel, Svenja Morsbach, Friederike Schmid, Dorothee Dormann, Lukas Stelzl, Martin Girard, Edward A. Lemke   +16 more
wiley   +1 more source

Ordered Chaos: Photoreceptor Mosaics in the Larval and Adult Turquoise Killifish (Nothobranchius furzeri). [PDF]

J Comp Neurol
Noel NCL.
europepmc   +1 more source

Postcard from Claribel Cone to Bernard Cone, September 29, 1904. Claribel Cone and Etta Cone Papers, Archives and Manuscripts Collections, The Baltimore Museum of Art. CP5.3.1

Postcard from Claribel Cone to Bernard Cone, September 29, 1904. Claribel asks her brother Bernard to get six copies of the New York Times for Sunday, March 6(?), 1904 which included an article by the physician Austin Flint.
Cone, Claribel, 1864-1929;
core  

Generation and Enhancement of Persistent Nanoscale Magnetization in All‐Dielectric Metasurfaces by Optically Injected and Localized Free Carriers

Advanced Science, EarlyView.
Infrared metasurface‐guided waves (IR‐MGW) scattered by a time interface (TI) induced by rapid, localized free‐carrier generation can be efficiently rectified to generate strong, persistent magnetic fields. We develop a rigorous, theoretical model to study a time‐varying, dispersive medium and uncover the redistribution of the initial energy of the IR ...
Shivaksh Rawat, Samyobrata Mukherjee, Gennady Shvets   +2 more
wiley   +1 more source

Functional and Structural Characterization of a Large Animal Model of RDH5-Associated Retinopathy. [PDF]

Transl Vis Sci Technol
Ford LM, Occelli LM, Enfield ME, Benjamin NA, Sun K, Pasmanter N, Petersen-Jones SM.   +6 more
europepmc   +1 more source

Self‐Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines

Advanced Science, EarlyView.
Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang, Min Li, Zhiying Yao, Yu Hu, Zhili Wang, Wendi Shi, Bingbing Sun   +6 more
wiley   +1 more source

Structural Colors from Modulated Topological Defects in Molecular Smectic Liquid Crystals

Advanced Science, EarlyView.
Rather than using dyes and pigments, nature produces the colors of some butterflies and beetles through optical interference phenomena. This study describes an original biomimetic strategy exploiting the spontaneous formation of modulated linear defects in thin films of 8CB, a common molecular liquid crystal.
Camille N. Mahyaoui, Guilhem Poy, Rabab Zehra, Axel Fouques, Vassili Sergan, Ivan Dozov, Claire Meyer, Patrick Davidson   +7 more
wiley   +1 more source

Genetic evidence and cross-species functional characterization implicate <i>CNN2</i> in age-related macular degeneration susceptibility. [PDF]

Proc Natl Acad Sci U S A
Cheng FF, Mou H, Liu Z, Zhang CJ, Zhuang YY, Wu Z, Wen XR, Xue A, Zhang X, Yang J, Jin ZB.   +10 more
europepmc   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Defining a Novel RPGR Phenotype of Sector Retinitis Pigmentosa With Cone Dystrophy. [PDF]

Invest Ophthalmol Vis Sci
Abdalla Elsayed MEA, Mahroo OA, Webster A, Tsang SH, Marques JP, Traboulsi E, Tan TE, Boon CJF, de la Camara CM, Fenner BJ, Barone V, Dollfus H, MacLaren RE.   +12 more
europepmc   +1 more source