Results 131 to 140 of about 294,373 (174)

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway

Advanced Science, EarlyView.
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie, Shang‐Hui Ye, Yu‐Ting Yue, Bao‐Hong Shi, Jing‐Ping Xu, Lian‐Jie Li, Zheng‐Biao Zou, Matthew B. Greenblatt, Na Li, Xian‐Wen Yang, Ren Xu   +10 more
wiley   +1 more source

Dynamic context-based updating of object representations in visual cortex

Aldegheri G, Gayet S, Peelen MV.
europepmc   +1 more source

Prediction of future input explains lateral connectivity in primary visual cortex. [PDF]

Curr Biol
Klavinskis-Whiting S, Fristed E, Singer Y, Iacaruso MF, King AJ, Harper NS.   +5 more
europepmc   +1 more source

Multi‐Shank 1024 Channels Active SiNAPS Probe for Large Multi‐Regional Topographical Electrophysiological Mapping of Neural Dynamics

Advanced Science, EarlyView.
This research article introduces a novel CMOS neural probe with 1024 channels distributed across eight shanks. The SiNAPS probe allows for the simultaneous recording of both local field potentials and action potentials in large brain areas. The probe's design allows for detailed mapping and linking neural dynamics and population unit activity, as ...
Gian Nicola Angotzi, Mihály Vöröslakos, Nikolas Perentos, Joao Filipe Ribeiro, Matteo Vincenzi, Fabio Boi, Aziliz Lecomte, Gabor Orban, Andreas Genewsky, Gerrit Schwesig, Deren Aykan, György Buzsáki, Anton Sirota, Luca Berdondini   +13 more
wiley   +1 more source

Multiple loci for foveolar vision in macaque monkey visual cortex. [PDF]

Nat Neurosci
Qian M, Wang J, Gao Y, Chen M, Liu Y, Zhou D, Lu HD, Zhang X, Hu JM, Roe AW.   +9 more
europepmc   +1 more source

Dynamic Pathophysiological Insight into the Brain by NIR‐II Imaging

Advanced Science, EarlyView.
The functional integration of benefits from small semiconducting dyes and biocompatible serum proteins ushered in a new frontier of deep wide‐field in vivo imaging technique, affording valuable pathophysiological insight into the functioning of neurovascular unit in space and time.
Si Chen, Hao Chen, Xinxin Li, Shuqing He, Kangquan Shou, Kun Qian, Zhao Fang, Feng Gu, Baisong Chang, Zhen Cheng   +9 more
wiley   +1 more source

The psychedelic psilocybin and light exposure have similar and synergistic effects on gene expression patterns in the visual cortex. [PDF]

Mol Brain
Harari R, Getselter D, Elliott E.
europepmc   +1 more source

A Rapid Cortical Learning Process Supporting Students’ Knowledge Construction During Real Classroom Teaching

Advanced Science, EarlyView.
There is growing interest in understanding how classroom teaching works, but previous theories and studies leave a gap in the neurocognitive mechanisms involved in real classroom teaching. Here we show that during real classroom teaching, students' middle frontal cortex serves as a hub of a rapid cortical learning process, supporting their knowledge ...
Xiaodan Feng, Xinran Xu, Zhaonan Meng, Jiahao Jiang, Miao Pei, Yonghe Zheng, Chunming Lu   +6 more
wiley   +1 more source

Ecological Trait Differences Are Associated with Gene Expression in the Primary Visual Cortex of Primates. [PDF]

Genes (Basel)
Zintel TM, Ely JJ, Raghanti MA, Hopkins WD, Hof PR, Sherwood CC, Kamilar JM, Bauernfeind AL, Babbitt CC.   +8 more
europepmc   +1 more source