Results 131 to 140 of about 4,427,249 (406)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Improving Deep Visual Representation for Person Re-identification by Global and Local Image-language Association [PDF]

open access: yesarXiv, 2018
Person re-identification is an important task that requires learning discriminative visual features for distinguishing different person identities. Diverse auxiliary information has been utilized to improve the visual feature learning. In this paper, we propose to exploit natural language description as additional training supervisions for effective ...
arxiv  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Inside the Image and the Word: the Re/membering of Indigenous Identities [PDF]

open access: yes, 2009
By appropriating the power of writing of the phonetic Latin alphabet and recent visual technology, new generations of indigenous people from the Americas have been able to articulate and reinforce their own sense of identity from within their cultural ...
Fachin, Dina
core   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

REBRANDING OF UNIVERSITY POLITEHNICA OF BUCHAREST

open access: yesJournal of Industrial Design and Engineering Graphics, 2018
In this paper is presented a concept of redesign of the logo of Politehnica University of Bucharest. The redesign process begins with the presentation of the current stage of visual identity, and continues with the processes of research, sketching and ...
Radu Mihail Sofrone
doaj   +2 more sources

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Teacher Education: Design Thinking Approach in Makerspaces to Produce Quality Educational Video Games with a Visual Identity and Improve Design Thinking Skills

open access: yesEducation Sciences
Video games participate effectively in the educational process due to their attractive visual features, but there are many challenges that teachers face when using them.
Yara Ahmed Mohebeldin Zaky   +1 more
doaj   +1 more source

Identifying factors affecting the creation of brand identity in Iran's banking industry [PDF]

open access: yesارزش آفرینی در مدیریت کسب و کار
The purpose of this research is to identify the factors influencing the creation of brand identity in the banking industry of Iran. According to its purpose, the research method is applicable, and in terms of implementation, it is qualitative and based ...
Seyed Mahdi Saatchi   +3 more
doaj   +1 more source

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