Results 51 to 60 of about 224,604 (235)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Evolutionary Trend of Graphic Design in the Packages of Famous Brands: The Case Study of Frito-Lay Inc Brand sin [PDF]

open access: yesپیکره, 2017
The graphic design of the brands evolves under the influence of a wide variety of factors such as shifting targets to sell more or, at least, to keep the market share of a given product as well as social and political parameters or technological advances.
Mansour Kolahkaj
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Communication design for cultural heritage: disclose the identity of Ascoli Piceno experimenting with signs and symbols

open access: yesDisegnare con, 2012
The Design for the valorisation of cultural heritage, activates some skills useful for initiating systemic processes integrated, promoting a more suitable interaction between the actors involved in the valuation of assets.
Federico Orfeo Oppedisano, Daniele Rossi
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

DESIGN AND REDESIGN OF THE VISUAL IDENTITY FOR THE FACULTY OF AEROSPACE ENGINEERING [PDF]

open access: yesFiabilitate şi Durabilitate
This project focuses on the redesign of the visual identity for the National University of Science and Technology Politehnica Bucharest and its Faculty of Aerospace Engineering.
C. LUCHIAN   +5 more
doaj  

The Rock-on-Iset Project as a Mechanism for Reconstructing Local Identity: From Underground to Urban Brand

open access: yesУправление культурой
This article analyzes the Rock-on-Iset Project as a mechanism for reconstructing local identity and transforming subcultural heritage into a territorial brand.
Ruslan E. Hisamutdinov   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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