Results 61 to 70 of about 211,587 (235)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Designing a brand identity model in the football industry

open access: yesRevista Brasileira de Futsal e Futebol, 2022
Today, football is one of the most popular sports globally. Its particular attractiveness is firmly linked to brand concepts; therefore, this study aimed to design a brand identity model in the football industry. This research applied in terms of purpose
Siavash Khodaparast   +2 more
doaj  

Between scenography and identity: Serbia in the Oriental Pavilion of the 1885 Budapest exhibition [PDF]

open access: yesBaština
This paper analyzes Serbia's participation in the Oriental Pavilion of the 1885. Budapest National Exhibition, a major cultural and economic event within the Austro-Hungarian Monarchy.
Frfulanović Dragana D.
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

(Re)faire Tracés

open access: yesTracés, 2018
Tracés’ visual identity lacks unity due to the inner constraints of its different medium formats (paper print, website, blog): colours, graphic composition, typographic fonts differ from one medium to another.
Sophie Pierret   +1 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Buildings from the Socialist Past as part of a City’s Brand Identity: The case of Warsaw

open access: yesBulletin of Geography. Socio-Economic Series, 2018
The aim of this paper is to investigate those buildings left over from Warsaw’s socialist past as a part of the city’s brand visual identity including their perception by foreign tourists and local citizens.
Ochkovskaya Marina   +1 more
doaj   +1 more source

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