Results 61 to 70 of about 211,587 (235)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Designing a brand identity model in the football industry
Today, football is one of the most popular sports globally. Its particular attractiveness is firmly linked to brand concepts; therefore, this study aimed to design a brand identity model in the football industry. This research applied in terms of purpose
Siavash Khodaparast +2 more
doaj
Between scenography and identity: Serbia in the Oriental Pavilion of the 1885 Budapest exhibition [PDF]
This paper analyzes Serbia's participation in the Oriental Pavilion of the 1885. Budapest National Exhibition, a major cultural and economic event within the Austro-Hungarian Monarchy.
Frfulanović Dragana D.
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Egg recognition: The importance of quantifying multiple repeatable features as visual identity signals. [PDF]
Gómez J, Gordo O, Minias P.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Tracés’ visual identity lacks unity due to the inner constraints of its different medium formats (paper print, website, blog): colours, graphic composition, typographic fonts differ from one medium to another.
Sophie Pierret +1 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Buildings from the Socialist Past as part of a City’s Brand Identity: The case of Warsaw
The aim of this paper is to investigate those buildings left over from Warsaw’s socialist past as a part of the city’s brand visual identity including their perception by foreign tourists and local citizens.
Ochkovskaya Marina +1 more
doaj +1 more source

