Results 81 to 90 of about 212,256 (235)
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Could changes in visual identity impact student attachment?
Universities increasingly use marketing and branding tools to appeal to prospective students, yet the role of visual identity in shaping how students and staff relate to their institution remains underexplored.
Radomír Masaryk +2 more
doaj +1 more source
SOME ASPECTS OF THE ROLE OF VISUAL IDENTITY IN THE SUCCESSFUL IMPLEMENTATION OF THE PROMOTIONAL STRATEGY [PDF]
This paper wishes to emphasize the necessity and importance of the communicational capital of a business, in the midst of fierce competition and bombarding of all clients with a great deal of data through classical methods of advertising.
Tarcza Teodora Mihaela
doaj
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Visualizing Entrepreneurship: A Semiotic Analysis of Brands and Identity Construction
Objective: This study explores the symbolic aspects of brand representation and how it aligns with the entrepreneurial spirit via the lens of semiotics.
Karl Ponteras Campos
doaj +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Design and Reconceptualization of the Visual Brand Identity Framework
Purpose – The aim of the paper is to redefine and conceptualize the essence and connections of visual brand identity through a new perspective. It begins with a critical examination of current visual brand identity theories, identifying and addressing ...
Nóra Julianna Gombos
doaj +1 more source

