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Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study
Lancet Global Health, 2020 Summary Background Many causes of vision impairment can be prevented or treated. With an ageing global population, the demands for eye health services are increasing.Jaimie D. Adelson, R. Bourne, P. Briant, S. Flaxman, H. Taylor, J. Jonas, Amir Abdoli, Woldu Aberhe Abrha, Ahmed Abualhasan, Eman Abu-Gharbieh, T. Adal, A. Afshin, H. Ahmadieh, W. Alemayehu, S. Alemzadeh, Ahmed Samir Alfaar, V. Alipour, S. Androudi, J. Arabloo, A. Arditi, Brhane Berhe Aregawi, A. Arrigo, Charlie Ashbaugh, E. Ashrafi, Desta Debalkie Atnafu, E. Bagli, A. Baig, T. Bärnighausen, M. Battaglia Parodi, Mahya Beheshti, A. Bhagavathula, Nikha Bhardwaj, P. Bhardwaj, Krittika Bhattacharyya, Ali Bijani, M. Bikbov, Michele Bottone, T. Braithwaite, A. Bron, Sharath Burugina Nagaraja, Z. Butt, F. L. Caetano dos Santos, Vera L James Carneiro, R. Casson, Ching-Yu Cheng, J. Choi, D. Chu, M. Cicinelli, J. Coelho, N. Congdon, Rosa A A Couto, E. Cromwell, Saad M A Dahlawi, X. Dai, R. Dana, L. Dandona, R. Dandona, M. D. Del Monte, Meseret Derbew Molla, Nikolaos Dervenis, A. Desta, J. Deva, Daniel Diaz, S. Djalalinia, Joshua R. Ehrlich, Rajesh Elayedath, H. Elhabashy, L. Ellwein, M. Emamian, S. Eskandarieh, F. Farzadfar, A. Fernandes, F. Fischer, D. Friedman, J. Furtado, Shilpa Gaidhane, G. Gazzard, Berhe Gebremichael, R. George, A. Ghashghaee, S. Gilani, Mahaveer Golechha, S. Hamidi, B. Hammond, M. Hartnett, R. K. Hartono, Abdiwahab Hashi, Simon Iain Hay, Khezar Hayat, G. Heidari, H. Ho, R. Holla, Mowafa J Househ, John J Emmanuel Huang, S. E. Ibitoye, I. Ilic, M. Ilic, April D Ingram, S. Irvani, S. Islam, Ramaiah Itumalla, S. Jayaram, Ravi Prakash Jha, R. Kahloun, R. Kalhor, Himal Kandel, Ayele Semachew Kasa, Taras Kavetskyy, G. Kayode, J. Kempen, M. Khairallah, Rovshan Khalilov, E. Khan, R. Khanna, M. Khatib, T. Khoja, Judy E. Kim, Y. Kim, Gyu Ri Kim, S. Kısa, A. Kisa, S. Kosen, A. Koyanagi, B. Kucuk Bicer, V. Kulkarni, O. Kurmi, I. Landires, V. Lansingh, J. Leasher, K. LeGrand, N. Leveziel, H. Limburg, Xuefeng Liu, Shilpashree Madhava Kunjathur, S. Maleki, N. Manafi, K. Mansouri, C. McAlinden, G. G. Meles, Abera Mersha, I. Michalek, T. Miller, S. Misra, Y. Mohammad, S. Mohammadi, Jemal Mohammed, A. Mokdad, M. A. Moni, A. Montasir, Alan R Fentaw Morse, G. F. Mulaw, M. Naderi, H. Naderifar, K. Naidoo, Mukhammad David Naimzada, V. Nangia, S. Narasimha Swamy, Dr Muhammad Naveed, Hadush Negash, Huong Lan Thi Nguyen, V. Núñez-Samudio, F. Ogbo, Kolawole T Ogundimu, A. Olagunju, O. Onwujekwe, Nikita Otstavnov, M. Owolabi, K. Pakshir, S. Panda-Jonas, Utsav Parekh, Eun-Cheol Park, Maja Pasovic, Shrikant Pawar, K. Pesudovs, T. Peto, H. Pham, M. Pinheiro, Vivek Podder, V. Rahimi-Movaghar, Mohammad Hifz Ur Rahman, P. Ramulu, P. Rathi, S. Rawaf, D. Rawaf, Lal B Rawal, Nickolas Reinig, A. Renzaho, A. Rezapour, A. Robin, Luca Rossetti, S. Sabour, S. Safi, A. Sahebkar, M. Sahraian, A. Samy, B. Sathian, G. Saya, M. Şaylan, A. Shaheen, M. Shaikh, T. Shen, K. Shibuya, W. Shiferaw, M. Shigematsu, J. Shin, J. Silva, Alex Silvester, J. Singh, Deepika Singhal, R. Sitorus, Eirini Skiadaresi, V. Skryabin, A. Skryabina, A. Soheili, M. B. Sorrie, R. A. Sousa, C. Sreeramareddy, Dwight Girma Stambolian, Eyayou Girma Tadesse, N. Tahhan, Md. Ismail Tareque, F. Topouzis, B. Tran, Gebiyaw K Tsegaye, M. Tsilimbaris, R. Varma, G. Virgili, Avina Vongpradith, G. Vu, Y. X. Wang, Ningli Hailay Wang, A. H. Weldemariam, S. West, Temesgen Gebeyehu Wondmeneh, T. Wong, M. Yaseri, N. Yonemoto, Chuanhua Yu, M. Zastrozhin, Zhi-Jiang Zhang, Stephanie R M Zimsen, S. Resnikoff, T. Vos +242 moresemanticscholar +1 more sourcePrevalence and factors associated with childhood visual impairment in Ethiopia [PDF]
, 2017 Lidiya Bezabih,1 Tilaye Workneh Abebe,1 Robera Olana Fite2 1Department of Public Health, College of Health Sciences, Adama General Hospital and Medical College, Adama, 2Department of Nursing, College of Medicine and Health Sciences, Wolaita Sodo ...Abebe TW, Fite RO, Bezabih Lcore Visual and health outcomes, measured with the activity inventory and the EQ-5D, in visual impairment [PDF]
, 2017 Purpose Generic instruments to assess health utilities can be used to express the burden of health problems in widely used indexes. That is in contrast with what can be obtained with condition-specific instruments, outcomes are very specific and ...Santana, Rui, Cima, Joana,, Baptista, António M. G., Joana Cima, António M. G. Baptista, Lima Ramos, Pedro,, Macedo, António Filipe, Marques, Ana Patricia,, Massof, Robert,, Moreno, Laura Hernández, Santana, Rui,, Rui Santana, Pedro Lima Ramos, Cima, Joana, Lima Ramos, Pedro, Robert Massof, Marques, Ana Patricia, Laura Hernandez-Moreno, Hernandez-Moreno, Laura, Antonio Filipe Macedo, Baptista, António M. G.,, Massof, Robert, Hernandez-Moreno, Laura,, Ramos, Pedro Alexandre Fernandes Lima, Macedo, António Filipe,, Ana Patricia Marques +25 morecore +1 more sourceSomatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen +5 morewiley +1 more sourceCauses of childhood blindness in the northeastern states of India. [PDF]
, 2008 BACKGROUND: The northeastern region (NER) of India is geographically isolated and ethno-culturally different from the rest of the country. There is lacuna regarding the data on causes of blindness and severe visual impairment in children from this region.Guha, Kamalesh, Gilbert, Clare, Borah, Rishi Raj, Das, Kalyan, Gogate, Parikshit, Purukayastha, S, Bhattacharjee, Harsha +6 morecore +1 more sourceEstablishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns +10 morewiley +1 more source