Results 111 to 120 of about 4,362,153 (359)

Visual Impairment and Blindness in Adults in the United States: Demographic and Geographic Variations from 2015 to 2050

open access: yesJAMA ophthalmology, 2016
Importance This paper describes the current and projected prevalence of visual impairment (VI) (visual acuity worse than 20/40, but better than 20/200) and blindness (visual acuity 20/200 or worse) in the United States.
R. Varma   +7 more
semanticscholar   +1 more source

Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study

open access: yesLancet Global Health, 2020
Summary Background Many causes of vision impairment can be prevented or treated. With an ageing global population, the demands for eye health services are increasing.
Jaimie D. Adelson   +242 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Prevalence and factors associated with childhood visual impairment in Ethiopia [PDF]

open access: yes, 2017
Lidiya Bezabih,1 Tilaye Workneh Abebe,1 Robera Olana Fite2 1Department of Public Health, College of Health Sciences, Adama General Hospital and Medical College, Adama, 2Department of Nursing, College of Medicine and Health Sciences, Wolaita Sodo ...
Abebe TW, Fite RO, Bezabih L
core  

Visual and health outcomes, measured with the activity inventory and the EQ-5D, in visual impairment [PDF]

open access: yes, 2017
Purpose Generic instruments to assess health utilities can be used to express the burden of health problems in widely used indexes. That is in contrast with what can be obtained with condition-specific instruments, outcomes are very specific and ...
Santana, Rui   +25 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Causes of childhood blindness in the northeastern states of India. [PDF]

open access: yes, 2008
BACKGROUND: The northeastern region (NER) of India is geographically isolated and ethno-culturally different from the rest of the country. There is lacuna regarding the data on causes of blindness and severe visual impairment in children from this region.
Guha, Kamalesh   +6 more
core   +1 more source

Stroke survivors’ views and experiences on impact of visual impairment

open access: yesBrain and Behavior, 2017
We sought to determine stroke survivors’ views on impact of stroke‐related visual impairment to quality of life.
F. Rowe
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Prevalence of visual impairment and severity of diabetic retinopathy in various ethnic groups in the UK [PDF]

open access: yes, 2011
Diabetic Retinopathy (DR) is a leading cause of visual impairment (VI) in the working population. Minor ethnic groups are at increased risk of diabetes.
Gupta, Bhaskar
core  

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