Results 31 to 40 of about 4,116,225 (362)

Involvement of the MEK-ERK/p38-CREB/c-fos signaling pathway in Kir channel inhibition-induced rat retinal Müller cell gliosis

open access: yesScientific Reports, 2017
Our previous studies have demonstrated that activation of group I metabotropic glutamate receptors downregulated Kir channels in chronic ocular hypertension (COH) rats, thus contributing to Müller cell gliosis, characterized by upregulated expression of ...
Feng Gao   +9 more
doaj   +1 more source

Evaluation of axial length/total corneal refractive power ratio as a potential marker for ocular diagnosis of Marfan’s syndrome in children [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
AIM: To investigate whether the axial length (AL)/total corneal refractive power (TCRP) ratio is a sensitive and simple factor that can be used for the early diagnosis of Marfan's syndrome (MFS) in children.
Tian-Hui Chen   +8 more
doaj   +1 more source

Daily functioning, problem solving and satisfaction for quality of life in visually impaired old persons [PDF]

open access: yes, 2017
Aim: The purpose of this study was to investigate the impact of several dimensions of functioning on satisfaction for quality of life (QoL) experienced by visually impaired older adults.
Carrieri, Loredana   +4 more
core   +1 more source

Nerve growth factor inhibits TLR3-induced inflammatory cascades in human corneal epithelial cells

open access: yesJournal of Inflammation, 2019
Background In herpes simplex epithelial keratitis, excessive TLR3-induced cellular responses after virus infection evoke inflammatory cascades that might be destructive to the host cornea. Nerve growth factor (NGF), a pluripotent neurotrophic factor with
Huiyu Chen   +3 more
doaj   +1 more source

Scleral ultrastructure and biomechanical changes in rabbits after negative lens application [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
AIM: To address the microstructure and biomechanical changes of the sclera of rabbits after negative lens application by spectacle frame apparatus. METHODS: Five New Zealand rabbits of seven weeks post-natal were treated with -8 D lens monocularly over ...
Xiao Lin   +8 more
doaj   +1 more source

Metabolomic Profiling of Aqueous Humor and Plasma in Primary Open Angle Glaucoma Patients Points Towards Novel Diagnostic and Therapeutic Strategy

open access: yesFrontiers in Pharmacology, 2021
Glaucoma is the second leading cause of blindness globally characterized by progressive loss of retinal ganglion cells (RGCs) and irreversible visual deficiency.
Yizhen Tang   +16 more
doaj   +1 more source

Monocular and binocular visual impairment in the UK Biobank study: prevalence, associations and diagnoses [PDF]

open access: yes, 2018
Objective; To determine the prevalence of, associations with and diagnoses leading to mild visual impairment or worse (logMAR >0.3) in middle-aged adults in the UK Biobank study.
Chou   +7 more
core   +1 more source

Vitreoretinal interface abnormalities in middle-aged adults with visual impairment in the UK Biobank study: prevalence, impact on visual acuity and associations [PDF]

open access: yes, 2017
Objective: The aim of this study was to determine the prevalence of vitreoretinal interface abnormalities (VRIA), the degree of visual impairment and associations with VRIA among adults, aged 40–69 years, in the UK Biobank study.
Farragher, T, McKibbin, M, Shickle, D
core   +1 more source

Playing Blind: Revealing the World of Gamers with Visual Impairment

open access: yesInternational Conference on Human Factors in Computing Systems, 2019
Previous research on games for people with visual impairment (PVI) has focused on co-designing or evaluating specific games - mostly under controlled conditions.
Ronny Andrade   +4 more
semanticscholar   +1 more source

Measurement of the depths at different regions of the anterior chamber in healthy Chinese adults [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To measure the depths of different regions of the anterior chamber (AC) in healthy Chinese adults, and to explore possible correlations with age or gender.
Yuan Zong   +5 more
doaj   +1 more source

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