Results 91 to 100 of about 103,804 (292)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Motor imagery based EEG features visualization for BCI applications

Procedia Computer Science, 2018
Abstract Over recent years, electroencephalography’s (EEG) use in the state-of-the-art brain-computer interface (BCI) technology has broadened to augment the quality of life, both with medical and non-medical applications. For medical applications, the availability of real-time data for processing, which could be used as command signals to control ...
Madiha Tariq, Pavel M. Trivailo, Milan Simic   +2 more
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Interactive Effects of Different Visual Imagery Perspectives and Narcissism on Motor Performance [PDF]

Journal of Sport and Exercise Psychology, 2010
Two studies examined the interactive effects of different visual imagery perspectives and narcissism on motor performance. In both studies participants completed the Narcissistic Personality Inventory (NPI-40: Raskin & Hall, 1979) and were assigned to either an internal visual imagery or external visual imagery group.
Ross, Roberts, Nichola, Callow, Lew, Hardy, Tim, Woodman, Laura, Thomas   +4 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The Promotoer: a successful story of translational research in BCI for motor rehabilitation [PDF]

, 2017
Several groups have recently demonstrated in the context of randomized controlled trials (RCTs) how sensorimotor Brain-Computer Interface (BCI) systems can be beneficial for post-stroke motor recovery.
Cincotti, Febo, Colamarino, Emma, Mattia, Donatella, Pichiorri, Floriana   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Motor and Visual Imagery as Two Complementary but Neurally Dissociable Mental Processes [PDF]

Journal of Cognitive Neuroscience, 2001
Abstract Recent studies indicate that covert mental activities, such as simulating a motor action and imagining the shape of an object, involve shared neural representations with actual motor performance and with visual perception, respectively.
A, Sirigu, J R, Duhamel
openaire   +2 more sources

Seeing with sound? Exploring different characteristics of a visual-to-auditory sensory substitution device [PDF]

, 2011
Sensory substitution devices convert live visual images into auditory signals, for example with a web camera (to record the images), a computer (to perform the conversion) and headphones (to listen to the sounds).
Bach-Y-Rita P, David Brown, Durette B, Evans K K, Jamie Ward, Marks L E, McKelvie S J, Tom Macpherson   +7 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source