Results 121 to 130 of about 664,902 (268)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Determinants of Non-infectious Scleritis Complications and Their Impact on Visual Outcome: Results from the International AIDA Network Scleritis Registry. [PDF]

Ophthalmol Ther
Sota J, Hinojosa-Azaola A, de-la-Torre A, Giardini HAM, Guerriero S, Kawakami-Campos PA, Martín-Nares E, Guaracha-Basañez GA, Ragab G, Chimenti MS, Lopalco G, Hissaria P, Cattalini M, Ruscitti P, Tharwat S, Ruiz-Irastorza G, García-Madero JJ, Tierradentro-Alape R, Hegazy MT, Afifi K, Emmi G, Parronchi P, Paroli MP, Hernández-Rodríguez J, Sainz-de-la-Maza M, Caggiano V, Sbalchiero J, Bugatti S, Gaggiano C, Breda L, Dammacco R, Monosi B, Capodiferro M, Beecher M, Olivieri AN, Batu ED, Ozen S, Frediani B, Thabet M, Balistreri A, Gupta V, Fonollosa A, Vitale A, Cantarini L, Fabiani C, Study Group of Systemic Autoinflammatory Disease of SIR (Italian Society of Rheumatology).   +45 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Visual outcome, safety, and complications of iris suture fixation versus iris claw fixation for aphakic correction: a prospective randomized study. [PDF]

BMC Ophthalmol
Saad EME, Mohammed HEM, Tharwat E, Sakr AM, Abdelhafeez SME, Yusef NM, Rashed MAA, Tawfik AMR, Alsadawy MAH, Abdou ARM, Okasha MG, Alabshihy MSI, Hussein ASA, Ghazala AMA, Abd Elkader GBH, Elhaw MAGM, Eldeen MAEMS, Ali MAA, Elsayed SSE, Sayed TGE.   +19 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Leveraging large scale deep learning models for diagnosis and visual outcome prediction in retinitis pigmentosa. [PDF]

NPJ Digit Med
Nagai T, Homma K, Kawamata Y, Yoshihara M, Kawakami E, Baba T.   +5 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Epidemiology and factors influencing visual outcome in paediatric ocular trauma at a tertiary health institution in Ghana. [PDF]

Ghana Med J
Beyuo VM, Braimah IZ, Abaidoo B, Lassey A, Essuman VA.   +4 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Visual outcome in hypermetropic eye post-refractive surgery: retrospective cohort study. [PDF]

Ann Med Surg (Lond)
Bamahfouz A, Alharbi E, Alqurashi A, Qasim O, Alsairafi J, Alsulami R, Aldaadi B, Alsaud R, Basheikh A.   +8 more
europepmc   +1 more source