Results 121 to 130 of about 4,664,382 (261)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Translating Visual to Textual Resources: Editorial and Technological Support for Electronic Publishing [PDF]

, 2020
This article is an extension of a presentation that occurred at the 2018 College Art Association, Visual Resources Association affiliate session in Los Angeles.
Burns, Maureen
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Eye Salvage and Vision Preservation in High‐Risk Intraocular Retinoblastoma Patients: Long‐Term Results From the Prospective Phase II AIEOP RTB 012 Study

Cancer Medicine
Introduction This study presents the outcomes of high‐risk group retinoblastoma (Rb) patients enrolled in the AIEOP RTB 012 Protocol. Methods Patients with intraocular unilateral Rb classified as group C/D according to “International Intraocular ...
Ida Russo, Valentina Di Ruscio, Maria Antonietta De Ioris, Giada Del Baldo, Maria Debora De Pasquale, Paola Valente, Enrico Opocher, Raffaele Parrozzani, Angela Di Giannatale, Maria Giuseppina Cefalo, Annalisa Serra, Giuseppe Maria Milano, Daniela Longo, Alessia Carboni, Rita De Vito, Gianluigi Natali, Gemma D'Elia, Gianni Bisogno, Angela Mastronuzzi, Raffaele Cozza, Rita Alaggio, Antonino Romanzo, Luca Buzzonetti, Franco Locatelli   +23 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Visual acuity outcome after cataract surgery (eyes) with available correction.

, 2013
aWHO classification of visual outcome after cataract surgery.
Francois Joubert (332095), Colin Cook (295262), Graeme Rogers (332098), David Steven (332091), Nicky Cockburn (332088), Sarah Polack (332101), Karin Lecuona (332093)   +6 more
core   +1 more source