The Goldfish as a Model for Studying Neuroestrogen Synthesis, Localization, and Action in the Brain and Visual System [PDF]
, 2011 Organizational and activational effects of estrogen (E) in the central nervous system (CNS) are exerted directly by circulating E and indirectly after aromatization of circulating androgen to E in the brain itself. Understanding an environmental chemical'
Betka, M., Callard, G. V., Kruger, A.
core +1 more source
Cerebello‐Prefrontal Connectivity Underlying Cognitive Dysfunction in Spinocerebellar Ataxia Type 2
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 2 (SCA2) is a hereditary cerebellar degenerative disorder, with motor and cognitive symptoms. The constellation of cognitive symptoms due to cerebellar degeneration is named cerebellar cognitive affective syndrome (CCAS), which has increasingly been recognized to profoundly impact patients' quality of life;
Ami Kumar +7 more
wiley +1 more source
Archives of Basic and Clinical ResearchObjective: The aim of our study is to evaluate whether there were any diffusion tensor imaging (DTI) parameter changes in the visual pathways in children with neuronal ceroid lipofuscinosis (NCL) for the early detection of visual pathway damage ...
Hafize Otcu Temur +4 more
doaj +1 more source
VISUAL DISTURBANCES RESULTING FROM LESIONS OF THE INTERCEREBRAL OPTIC PATHWAYS AND OF THE CORTICAL VISUAL SPHERE INGUNSHOT WOUNDS OF THE HEAD [PDF]
, 1920 P. Marie, n Chateli
openalex +1 more source
Deep Learning for Visual Neuroprosthesis [PDF]
arXivThe visual pathway involves complex networks of cells and regions which contribute to the encoding and processing of visual information. While some aspects of visual perception are understood, there are still many unanswered questions regarding the exact mechanisms of visual encoding and the organization of visual information along the pathway.
arxiv
Semantic and Contrast-Aware Saliency [PDF]
arXiv, 2018 In this paper, we proposed an integrated model of semantic-aware and contrast-aware saliency combining both bottom-up and top-down cues for effective saliency estimation and eye fixation prediction. The proposed model processes visual information using two pathways.
arxiv
Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier +8 more
wiley +1 more source
Differential functional reorganization of ventral and dorsal visual pathways following childhood hemispherectomy. [PDF]
Dev Cogn Neurosci, 2023 Ayzenberg V +4 more
europepmc +1 more source
Petri-net modeling of B-cell receptor signaling pathways: A case study in CLL [PDF]
arXiv, 2019 Immunology is the emerging research area which deals with the study of the immune system in any living organism. It is modelled through various computational and mathematical models to deal with the problem facing while to boost the immune system of an organism or to fight with the infectious disease at the very initial stage.
arxiv
Arthritis Care &Research, EarlyView.Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner +12 more
wiley +1 more source