Results 51 to 60 of about 23,423 (215)

Introducing multiple factor analysis (MFA) as a diagnostic taxonomic tool complementing principal component analysis (PCA) [PDF]

open access: yesZooKeys
Multiple factor analysis (MFA) is introduced as a diagnostic tool for taxonomy and discussed using examples from the herpetological literature. Its methodology and output are compared and contrasted to the more often used principal component analysis ...
L. Lee Grismer
doaj   +3 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Comparing Freshwater eDNA With Conventional Survey Methods to Detect Vertebrate Biodiversity in a Malagasy Tropical Rainforest

open access: yesEnvironmental DNA
Madagascar is globally recognized for its exceptional biodiversity and endemism yet remains severely under‐sampled for many taxa. We evaluate the effectiveness of environmental DNA (eDNA) metabarcoding as a rapid, non‐invasive method for surveying ...
Christina Biggs, Cosmo Le Breton
doaj   +1 more source

An Empirical Taxonomy of Video Summarization Model From a Statistical Perspective

open access: yesIEEE Access
This paper has thrown out a comprehensive taxonomic view of all different video summarization techniques that show variously adopted methodologies efficiently condensing large video data. The review categorizes and evaluates techniques against their core
Sai Babu Veesam, Aravapalli Rama Satish
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Mathematical activities and critical thinking ability in Lagosi weaving process of the Buginese community

open access: yesJournal of Honai Math
Lagosi, a renowned woven fabric of national significance, involves a precise calculation formula in its manufacturing process. Craftsmen must meticulously count the threads to ensure the motif aligns with the intended design. Despite its importance, this
Hikmawati Pathuddin   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Cases of endophthalmitis caused by Candida albicans and Candida dubliniensis identified via internal transcribed spacer deep sequencing

open access: yesBMC Ophthalmology
Background We report two cases of fungal endophthalmitis induced by Candida species identified based on internal transcribed spacer 1 (ITS1) sequencing. Case presentation In two cases, endophthalmitis was suspected, and the patients underwent pars plana ...
Kazunobu Asao   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

A realistic simulation-based benchmark of microbiome normalization in sample stratification and taxa-level analysis

open access: yesFrontiers in Bioinformatics
MotivationNormalization is a critical step in microbiome studies because sequencing depth and sparsity can strongly affect downstream analyses. In real datasets, however, the underlying biological signal is unknown, making it difficult to determine ...
Amen Al Khafaji   +7 more
doaj   +1 more source

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