Results 21 to 30 of about 2,978 (120)

Rational Design of Multifunctional Tacrine Derivatives as Candidates for the Treatment of Alzheimer and Parkinson Diseases

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
We present a set of multifunctional tacrine derivatives, designed with the CADMA‐Chem protocol, aimed for Alzheimer and Parkinson diseases. Of the tacrines designed, TAC‐674 and TAC‐678 are the best candidates to act as multifunctional antioxidants and neuroprotectors for Alzheimer and Parkinson diseases, respectively.
Eugenia Dzib, Luis Felipe Hernández‐Ayala, Silvana Silva‐Aguirre, Annia Galano   +3 more
wiley   +1 more source

Diversidad y geometría en la ESO : el caso de alumnado deficiente auditivo

Contextos Educativos: Revista de Educación, 2013
The aim of the research conducted by the AUDIMAT Project since 2001, is to recognise and assess deaf students’ difficulties in regular inclusive classrooms to achieve their mathematics (geometry) learning with as similar results as hearing pairs.
Núria Rosich, Joaquín Jiménez, Rosa M. Latorre, Sergi Muria   +3 more
doaj   +1 more source

WFX Molecular Fragment References for Hirshfeld Charge‐Transfer Analysis in Non‐Covalent Complexes

Journal of Computational Chemistry, Volume 47, Issue 20, July 30, 2026.
The choice of reference state strongly affects Hirshfeld charge‐transfer analysis. Atomic references predict substantially larger intermolecular charge transfer than molecular fragment WFX references in non‐covalent complexes. ABSTRACT In this work, we introduce and assess a fragment‐based Hirshfeld scheme in which molecular WFX files of isolated ...
Jorge Garza, Rubicelia Vargas
wiley   +1 more source

“Data objetos”: Diseño de productos para el diálogo y la movilización de conciencias

Academia XXII, 2019
Este artículo expone e ilustra las oportunidades que existen para los diseñadores industriales en el diseño de objetos tridimensionales y tangibles que representen datos.
Ricardo Sosa Medina
doaj   +1 more source

NMR‐Based Structural Analysis of Highly Substituted Pyridines From Kondrat'eva Aza‐Diels–Alder Cycloadditions

Magnetic Resonance in Chemistry, Volume 64, Issue 3, Page 324-332, March 2026.
We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno, Francisco Méndez, Atilano Gutierrez‐Carrillo, Mónica A. Rincón‐Guevara, Yoarhy A. Amador‐Sánchez, Alejandro Islas‐Jácome, Eduardo González‐Zamora   +6 more
wiley   +1 more source

Periodismo de datos y prensa nativa digital: cobertura de la campaña electoral del 10N a través de El Confidencial, Eldiario.es y El Español

Doxa Comunicación, 2021
El volumen de datos tan grande al que podemos tener acceso hoy en día hace que nos encontremos con un nuevo escenario mediático. El periodismo de datos supone un modo distinto de contar historias, una narrativa visual que combina los datos con las ...
Ana Virginia Rubio Jordán
doaj   +1 more source

Endometrial assessment in abnormal uterine bleeding: transvaginal ultrasound alone may not be good enough

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 1, Page 79-88, January 2026.
ABSTRACT Objective To evaluate the proportion of optimal assessments of endometrial thickness (ET) achieved by transvaginal ultrasound (TVS) compared with a multimodal (MM) sonographic approach in women with abnormal uterine bleeding (AUB). Methods This prospective observational study was a subset of the EPI‐SURE study conducted between June and ...
S. Nijjar, S. Kastora, A. Bajrami, S. Solangon, M. Widschwendter, D. Jurkovic   +5 more
wiley   +1 more source

From Free‐Standing to Textile Electrodes: Carbonaceous Biocompatible Material for Wearable Sensing

Healthcare Technology Letters, Volume 13, Issue 1, January/December 2026.
This work introduces a sustainable and cost‐effective method for fabricating biocompatible carbon‐based electrodes using a custom carbon black–chitosan ink enhanced with carbon nanotubes. These electrodes demonstrate excellent conductivity, mechanical durability, and long‐term biocompatibility with the use of any conductive gel, making them ideal for ...
Marta Vegas‐García, Anandapadmanabhan Ambily Rajendran, Beatriz L. Garrote, Daniel Valero Beltrá, Laura García‐Carmona, Alfredo Quijano‐López, Marta García‐Pellicer   +6 more
wiley   +1 more source

Modelos mentales y algoritmos de programación en estudiantes de media técnica en informática

Revista Virtual Universidad Católica del Norte, 2023
El presente artículo analiza la asociación entre la tipología de estructuras algorítmicas de programación y los modelos mentales construidos para su resolución. El estudio se inscribe en el paradigma cuantitativo con un diseño cuasi-experimental, y contó
Yazmín Eliana Cifuentes Osorio, Ingrid Durley Torres Pardo, Marta González Gil   +2 more
doaj   +1 more source

Impact of C18 Epimerization of Indole‐ and Pyrazole‐Fused 18β‐Glycyrrhetinic Acid Derivatives on PTP1B and TCPTP Inhibitory Activity: Synthesis, In Vitro, and In Silico Studies

ChemMedChem, Volume 20, Issue 22, November 18, 2025.
The indole derivative (FC‐114) and the N‐phenylpyrazole (FC‐122) of glycyrrhetinic acid are both potent inhibitors of the Protein Tyrosine Phosphatase 1B, with IC50 values of 0.48 μM and 1.15 μM, respectively. However, their activity decreases by up to four times when the 18β‐H position is epimerized to 18α‐H or when the carbonyl group at the C11 ...
Ledy De‐la‐Cruz‐Martínez, Rosendo Martínez‐Arellano, Mitzi López‐Sánchez, José G. Alvarado‐Rodríguez, Jesús Martin Torres‐Valencia, David Equihua‐González, Julio‐César Almanza‐Pérez, Jaime Pérez‐Villanueva, Martín González‐Andrade, José C. Páez‐Franco, Francisco Cortés‐Benítez   +10 more
wiley   +1 more source