Results 51 to 60 of about 1,464,252 (288)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Developing Effective Community Network Analysis Tools According to Visualization Psychology [PDF]

open access: yesarXiv, 2020
Visualization is a useful technology in health science, and especially for community network analysis. Because visualization applications in healthcare are typically risk-averse, health psychologists can play a significant role in ensuring appropriate and effective uses of visualization techniques in healthcare.
arxiv  

Visual attention information can be traced on cortical response but not on the retina: evidence from electrophysiological mouse data using natural images as stimuli [PDF]

open access: yesarXiv, 2023
Visual attention forms the basis of understanding the visual world. In this work we follow a computational approach to investigate the biological basis of visual attention. We analyze retinal and cortical electrophysiological data from mouse. Visual Stimuli are Natural Images depicting real world scenes.
arxiv  

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Visualization and selection of Dynamic Mode Decomposition components for unsteady flow

open access: yesVisual Informatics, 2021
Dynamic Mode Decomposition (DMD) is a data-driven and model-free decomposition technique. It is suitable for revealing spatio-temporal features of both numerically and experimentally acquired data.
T. Krake   +4 more
doaj  

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Assessment of Turbulence Models over a Curved Hill Flow with Passive Scalar Transport

open access: yesEnergies, 2022
An incoming canonical spatially developing turbulent boundary layer (SDTBL) over a 2-D curved hill is numerically investigated via the Reynolds-averaged Navier–Stokes (RANS) equations plus two eddy-viscosity models: the K−ω SST (henceforth SST) and the ...
David Paeres   +2 more
doaj   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Measuring Effects of Spatial Visualization and Domain on Visualization Task Performance: A Comparative Study [PDF]

open access: yesarXiv, 2022
Understanding your audience is foundational to creating high impact visualization designs. However, individual differences and cognitive abilities also influence interactions with information visualization. Differing user needs and abilities suggest that an individual's background could influence cognitive performance and interactions with visuals in a
arxiv  

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