Results 61 to 70 of about 1,464,252 (288)

Generative Adversarial Networks for Morphological–Temporal Classification of Stem Cell Images

Sensors, 2021
Frequently, neural network training involving biological images suffers from a lack of data, resulting in inefficient network learning. This issue stems from limitations in terms of time, resources, and difficulty in cellular experimentation and data ...
Adam Witmer, Bir Bhanu
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

A visualization system for intelligent diagnosis and statistical analysis of oral diseases based on panoramic radiography

Scientific Reports
Panoramic radiography is an essential auxiliary diagnostic tool for oral diseases. It is a difficult and time-consuming task to conduct extensive panoramic radiography interpretation. These challenges are exacerbated by the creation of electronic medical
Yue Hong, Tianya Pan, Shenji Zhu, Miaoxin Hu, Zhiguang Zhou, Ting Xu   +5 more
doaj   +1 more source

Visual assessment of biliary excretion of Gd-EOB-DTPA in patients with suspected diffuse liver disease – A biopsy-verified prospective study

European Journal of Radiology Open, 2015
Objectives: To qualitatively evaluate late dynamic contrast phases, 10, 20 and 30 min, after administration of Gd-EOB-DTPA with regard to biliary excretion in patients presenting with elevated liver enzymes without clinical signs of cirrhosis or hepatic ...
Bengt Norén, Nils Dahlström, Mikael Fredrik Forsgren, Olof Dahlqvist Leinhard, Stergios Kechagias, Sven Almer, Staffan Wirell, Örjan Smedby, Peter Lundberg   +8 more
doaj   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Surveying Wonderland for many more literature visualization techniques [PDF]

arXiv, 2021
There are still many potential literature visualizations to be discovered. By focusing on a single text, the author surveys many existing visualizations across research domains, in the wild, and creates new visualizations. 58 techniques are indicated, suggesting a wider variety of visualizations beyond research disciplines.
arxiv  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Solution-processed MAPbI3/Cs2AgBiBr6 heterostructure through epitaxial growth for broadband photo-detection

APL Materials, 2022
All-inorganic halide semiconductors with perovskite or perovskite-like structure have aroused a widespread concern recently for its environmental friendliness and stabilities while possessing excellent optoelectronic properties.
Mengrou Wang, Yubing Xu, Xin Wang, Yuwei Li, Jingda Zhao, Yuzhu Pan, Jing Chen, Qing Li, Zhiwei Zhao, Jun Wu, Wei Lei   +10 more
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Transfer Learning via Unsupervised Task Discovery for Visual Question Answering [PDF]

arXiv, 2018
We study how to leverage off-the-shelf visual and linguistic data to cope with out-of-vocabulary answers in visual question answering task. Existing large-scale visual datasets with annotations such as image class labels, bounding boxes and region descriptions are good sources for learning rich and diverse visual concepts.
arxiv