Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
New observables for multiple-parton interactions measurements using Z + jets process at the LHC
Multiple-parton interactions play a vital role in hadron-hadron collisions. This paper presents a study of the multiple-parton interactions with simulated Z + jets events in proton-proton collisions at a centre-of-mass energy of 13 TeV.
Bansal, M. +3 more
core +1 more source
Debating critical costume: negotiating ideologies of appearance, performance and disciplinarity [PDF]
In this article, I present an argument for a proposed focus of ‘critical costume’. Critical Costume, as a research platform, was founded in 2013 to promote new debate and scholarship on the status of costume in contemporary art and culture.
Hann, Rachel
core +2 more sources
Returns to Late Aged College Degrees
The benefits of a college education are well documented. However, the majority of existing research focuses on students who matriculate soon after high school graduation.
Sally Wallace +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Evaluation of a village-informant driven demographic surveillance system in Karonga, Northern Malawi [PDF]
This paper describes and evaluates the first demographic surveillance system (DSS) in Malawi, covering a rural population of 30,000. Unlike others, the Karonga DSS relies on trained village informants using formatted registers for the primary ...
Amelia Crampin +9 more
core
Generating Narrative Spaces from Events History [PDF]
For a successful distributed teamwork it is vital to provide team-members with awareness on collaborative activities. One way of achieving this is through applying a narrative based approach to construct the events that have taken place on documents and ...
Fatah gen Schieck, A +2 more
core
LHC Signatures of Two-Higgs-Doublets with Fourth Family
On-going Higgs searches in the light mass window are of vital importance for testing the Higgs mechanism and probing new physics beyond the standard model (SM).
Chen, Ning, He, Hong-Jian
core +1 more source
A Typology of Transition-Age Youth
Young adulthood is a time of transition which poses particular challenges for youth who are homeless or at risk of homelessness, including those exiting foster care.
Jessica Raithel +3 more
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source

