Results 71 to 80 of about 1,938,986 (286)

FLIAT, an object-relational GIS tool for flood impact assessment in Flanders, Belgium [PDF]

, 2019
Floods can cause damage to transportation and energy infrastructure, disrupt the delivery of services, and take a toll on public health, sometimes even causing significant loss of life. Although scientists widely stress the compelling need for resilience
Beullens, Jochem, De Maeyer, Philippe, De Wulf, Alain, Van Ackere, Samuel, Vanneuville, Wouter   +4 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Landscape-scale drivers of glacial ecosystem change in the montane forests of the eastern Andean flank, Ecuador [PDF]

, 2018
Understanding the impact of landscape-scale disturbance events during the last glacial period is vital in accu- rately reconstructing the ecosystem dynamics of montane environments. Here, a sedimentary succession from the tropical montane cloud forest of
Aalto, Angela L. Coe, Baker, Bakker, Bennett, Bennett, Blunier, Bogotá-A, Bond, Bronk Ramsey, Bruijnzeel, Bush, Bush, Bush, Bussmann, Campbell, Churchill, Clark, Clark, Coblentz, Colinvaux, Colinvaux, Colinvaux, Coltorti, Corlett, Crausbay, Cugny, Cárdenas, Cárdenas, Daniau, Davis, Encarni Montoya, Enzweiler, Faegri, Fahey, Galeas, Gelorini, Gill, Gosling, Gosling, Gosling, Grau, Groot, Grubb, Grubb, Grubb, Hall, Hamilton, Hanselman, Harling, Heiri, Hooghiemstra, Juggins, Keen, Krug, Liu, Loughlin, López-Vila, Marchant, Marshall, Mayle, Montoya, Montoya, Moore, Mosblech, Mourguiart, Neill, Neill, Newnham, Nicholas J.D. Loughlin, Patricia Mothes, Pauline Gulliver, Reimer, Roubik, Rull, Rull, Rull, Rull, Sanchez Goñi, Sarmiento, Sarmiento, Sierra, Stern, Stockmarr, Thomas, Urrego, Urrego, Urrego, Valencia, Valencia, van der Hammen, van der Werf, van Geel, van Geel, van Geel, van Geel, van Geel, van Geel, van Geel, van Smeerdijk, Vandergoes, Webster, Weng, Weng, Whitlock, William D. Gosling, Williams   +106 more
core   +5 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Use of a continuous single lead electrocardiogram analytic to predict patient deterioration requiring rapid response team activation.

PLOS Digital Health
Identifying the onset of patient deterioration is challenging despite the potential to respond to patients earlier with better vital sign monitoring and rapid response team (RRT) activation.
Sooin Lee, Bryce Benson, Ashwin Belle, Richard P Medlin, David Jerkins, Foster Goss, Ashish K Khanna, Michael A DeVita, Kevin R Ward   +8 more
doaj   +1 more source

Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: long-term safety and efficacy in patients with rheumatoid arthritis [PDF]

, 2018
Objective: Mavrilimumab, a human monoclonal antibody, targets granulocyte-macrophage colony-stimulating factor receptor alpha. We report mavrilimumab long-term safety and efficacy in rheumatoid arthritis patients in two phase IIb studies (1071, 1107 ...
Achuthan, Akagawa, Aletaha, Aletaha, Antoniu, Avci, Berghen, Borg, Borie, Brown, Buch, Burmester, Burmester, Calisto, Cella, Chen, Cook, Cornish, Cottin, Crotti, Dawson, Felson, Fleetwood, Fries, Greven, Guo, Hamilton, Jaguin, Kelly, Khan, Lazaro, Listing, Minter, Prevoo, Shaw, Shibata, Singh, Tsuchiya, Van der Heijde, Van Gestel, Van Onna, Ware, Weinblatt, Yoshida, Zhan   +44 more
core   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

The Unseen Bedrock of Global Health Law: Putting Civil Registration and Vital Statistics at the Core of the Global Health Law Agenda

AJIL Unbound
Civil registration and vital statistics (CRVS) systems comprise two interdependent components: civil registration (CR) and vital statistics (VS). Civil registration records the occurrence and characteristics of vital events in a population, including ...
Kriti Sharma, Margherita Melillo, Robert Eckford   +2 more
doaj   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Integrated information system for demographic statistics ´ESGRAON-TDS´ in Bulgaria [PDF]

In this paper we describe the Bulgarian statistical system that provides unique research possibilities for demographic analyses. In particular, we review the methodology, structure and informational flows for population registration and the registration ...
Iliana Kohler, Jordan Kaltchev, Mariana Dimova   +2 more
core   +3 more sources