Results 91 to 100 of about 1,938,986 (286)

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Populační vývoj Česka v roce 2023

Demografie
The article describes demographic development in Czechia during 2023 and sets it in the context of the previous five years. It focuses on both population stock and the main demographic processes, namely fertility, mortality, nuptiality, the divorce rate,
Jana Koukalová
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Demografické stárnutí v Česku mezi lety 2012–2022 prostřednictvím vybraných retrospektivních a prospektivních ukazatelů

Demografie
Demographic ageing is considered a significant phenomenon and one of the most important population issues of the 21st century. It is a process that has no parallel in human history but is completely natural.
Filip Čábela, Luděk Šídlo
doaj   +1 more source

Empirical Study of Privacy Issues Among Social Networking Sites. [PDF]

, 2010
Social media networks are increasing their types of services and the numbers of users are rapidly growing. However, online consumers have expressed concerns about their personal privacy protection and recent news articles have shown many privacy breaches
Kuzma, Joanne
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Analýza faktorů asociovaných s vícečetnými příčinami smrti v Česku v roce 2018 pomocí XGBoost regrese a metody SHAP

Demografie
This study focuses on the factors that are associated with recording multiple causes as the cause of death in Czechia. An XGBoost multiple regression is used in the analysis and its results are interpreted with SHAP values.
Bety Ukolova, Boris Burcin
doaj   +1 more source

Theory and practice of microlensing lightcurves around fold singularities

, 2003
Among all galactic microlensing events, those involving a passage of the observed source star over the caustic created by a binary lens are particularly useful in providing information about stellar atmospheres, the dynamics of stellar populations in our
Abe, Afonso, Afonso, Afonso, Afonso, Albrow, Albrow, Albrow, Albrow, Albrow, Albrow, Albrow, Alcock, Alcock, Alcock, Alcock, An, Cassan, Castro, Di Stefano, Di Stefano, Dominik, Dominik, Dominik, Dominik, Dominik, Dominik, Dominik, Fields, Gaudi, Gaudi, Gould, Gradshteyn, Hardy, Jaroszyński, M. Dominik, Mao, Mao, Rhie, Schneider, Schneider, Schneider, Schneider, Schneider, Schneider, Sumi, Udalski, Udalski, Witt, Woźniak, Yoo   +50 more
core   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Open science and phenotyping in UK administrative health, education and social care data: the ECHILD phenotype code list repository

International Journal of Population Data Science
Administrative health data, such as the Hospital Episode Statistics (HES), can be used to identify groups of people with a particular target condition, a process known as phenotyping.
Matthew A Jay, Kate Lewis, Difei Shi, Rebecca Langella, Tony Stone, Sorcha Ní Chobhthaigh, Ania Zylbersztejn, Ruth Blackburn, Katie Harron   +8 more
doaj   +1 more source