Results 61 to 70 of about 6,323,608 (321)

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

State Variation Mining: On Information Divergence with Message Importance in Big Data

, 2018
Information transfer which reveals the state variation of variables usually plays a vital role in big data analytics and processing. In fact, the measures for information transfer could reflect the system change by use of the variable distributions ...
Fan, Pingyi, Liu, Shanyun, She, Rui
core   +1 more source

Quantifying the impact of climate change on drought regimes using the Standardised Precipitation Index [PDF]

, 2015
The study presents a methodology to characterise short- or long-term drought events, designed to aid understanding of how climate change may affect future risk.
B Lehner, B Lloyd-Hughes, D Wilhite, D-W Kim, DGC Kirono, EJ Burke, EJ Burke, F Giorgi, H Wu, H-R Byun, IPCC, IPCC, IPCC, J Keyantash, J Sheffield, J Sheffield, JA Marengo, JH Christensen, JP Vidal, K Jenkins, K Rupa Kumar, Katie Jenkins, KT Redmond, L Vasiliades, M Weiβ, M Zhao, NB Guttman, NB Guttman, Q Mu, R Warren, R Warren, Rachel Warren, S Blenkinsop, T Barker, TD Mitchell, TD Mitchell, W Li, X Gao, X Zhang, Y Hirabayashi   +39 more
core   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

FLIAT, an object-relational GIS tool for flood impact assessment in Flanders, Belgium [PDF]

, 2019
Floods can cause damage to transportation and energy infrastructure, disrupt the delivery of services, and take a toll on public health, sometimes even causing significant loss of life. Although scientists widely stress the compelling need for resilience
Beullens, Jochem, De Maeyer, Philippe, De Wulf, Alain, Van Ackere, Samuel, Vanneuville, Wouter   +4 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Safety, tolerability, and impact on allergic inflammation of autologous E.coli autovaccine in the treatment of house dust mite asthma - a prospective open clinical trial [PDF]

, 2011
Background: Asthma is increasing worldwide and results from a complex immunological interaction between genetic susceptibility and environmental factors. Autovaccination with E.
AE Wright, American Thoracic Society, B Okrasinska-Cholewa, Bianca Weigand, E Zaluga, H Renz, J Halasa, J Halasa, J Kleine-Tebbe, J Rubisz-Brzezinska, Johannes Schulze, K Wilczynski, KJ Drachenberg, M Martin, Markus A Rose, MJ Abramson, NM Berezhnaia, O Nolte, PM Kay, R Schubert, Ralf Schubert, Stefan Zielen, T Zielinski, V Rusch, VF Filatov, Z Novotny   +25 more
core   +3 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Climate Change and Eutrophication: A Short Review [PDF]

, 2018
Water resources are vital not only for human beings but essentially all ecosystems. Human health is at risk if clean drinking water becomes contaminated.
Ahmad, Sajjad, Karakouzian, Moses, Nazari-Sharabian, Mohammad   +2 more
core   +2 more sources