Results 71 to 80 of about 470,833 (307)

Mining intensive care vitals for leading indicators of adverse health events [PDF]

Emerging Health Threats Journal, 2011
p components form a null space model of the expected normal behavior of the given vital sign. We build one null space model for each channel separately; this concludes the learning stage of the process. Each newly observed set of k consecutive measurements is then processed through Fourier transform and projected onto the p principal components of the ...
Roman Garnett, Madalina Fiterau, Artur Dubrawski, Rajas Lonkar   +3 more
openaire   +1 more source

Boundary identification of events in clinical named entity recognition [PDF]

arXiv, 2013
The problem of named entity recognition in the medical/clinical domain has gained increasing attention do to its vital role in a wide range of clinical decision support applications. The identification of complete and correct term span is vital for further knowledge synthesis (e.g., coding/mapping concepts thesauruses and classification standards ...
arxiv  

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Aplicação da análise exploratória espacial na identificação de configurações territoriais

Revista Brasileira de Estudos de População, 2011
A análise exploratória de dados espaciais, empregada para identificação de arranjos urbano-regionais entre os municípios brasileiros, mostrou-se adequada a estudos de conjuntos amplos de unidades observacionais (áreas), possibilitando resultados ...
Rosa Moura, Sachiko Araki Lira
doaj   +1 more source

Urban-rural differentials in Latin American infant mortality

Demographic Research, 2020
Background: Infant mortality in Latin America has declined dramatically over the past six decades. The health transition in the region began in the main cities and has tended to proceed more rapidly in countries with higher levels of urbanization ...
Jenny Garcia
doaj   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

The validity of astrological predictions on marriage and divorce: a longitudinal analysis of Swedish register data

Genus, 2020
This paper examines astrology, a concept that is considered unscientific by broad segments of the population in the western world. Despite this, astrology remains for some an important source for advice regarding choices in a range of different matters ...
Jonas Helgertz, Kirk Scott
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Deep Convolutional Neural Network for Roadway Incident Surveillance Using Audio Data [PDF]

arXiv, 2022
Crash events identification and prediction plays a vital role in understanding safety conditions for transportation systems. While existing systems use traffic parameters correlated with crash data to classify and train these models, we propose the use of a novel sensory unit that can also accurately identify crash events: microphone.
arxiv  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source