Results 71 to 80 of about 6,250,860 (324)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
DNA topoisomerases participate in fragility of the oncogene RET [PDF]
, 2013 Fragile site breakage was previously shown to result in rearrangement of the RET oncogene, resembling the rearrangements found in thyroid cancer. Common fragile sites are specific regions of the genome with a high susceptibility to DNA breakage under ...
A Ganguly +86 more
core +3 more sources
Clinical validation of
, 2023 Marcin Barczyński, Aleksander Konturek
openalex +1 more source
Vital event of servise of Vicentas Sladkevičius in 1956-1959
Genocidas ir rezistencija, 2021 The article analyses in detail and gives a factual account of the particularly important period of ministry of the famous Lithuanian Catholic clergyman Sladkevičius, i.e. 1956–1959. The atheistic secular government exercised strict control and dictatorship over the most important affairs of the religious communities, dealt with the appointment of the ...
openaire +1 more source
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
The socially organized basis of everyday ‘economic’ conduct: evidence from video recordings of real-life pre-verbal salesperson-shopper encounters in a showroom retail store [PDF]
, 2009 This paper reports the results of an analysis of the ways shoppers regularly occasioned (or attempted to occasion) or avoided (or attempted to avoid) verbal encounters with salespersons in a retail store. These everyday events are of vital importance for
Clark, Colin, Pinch, Trevor
core +1 more source
FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Resuscitation PlusAim: Although early detection of patients’ deterioration may improve outcomes, most of the detection criteria use on-the-spot values of vital signs. We investigated whether adding trend values over time enhanced the ability to predict adverse events ...
Rimi Tanii +6 more
doaj +1 more source
The effect of combined sewer overflow (CSO) on the abundance of antibiotic resistant bacteria in the James River [PDF]
, 2017 Antibiotics have been used to treat bacterial infections worldwide since their discovery in the early 20th century and are vital to human health. Unfortunately, the heavy use of antibiotics has led to the increased natural selection of antibiotic ...
Franklin, Rima B +2 more
core +1 more source