Results 81 to 90 of about 6,323,608 (321)

The effect of combined sewer overflow (CSO) on the abundance of antibiotic resistant bacteria in the James River [PDF]

, 2017
Antibiotics have been used to treat bacterial infections worldwide since their discovery in the early 20th century and are vital to human health. Unfortunately, the heavy use of antibiotics has led to the increased natural selection of antibiotic ...
Franklin, Rima B, Levengood, Enjolie, Moezzi, Sunauz   +2 more
core   +1 more source

Further Analyses of the Safety of Verubecestat in the Phase 3 EPOCH Trial of Mild-To-Moderate Alzheimer’s Disease [PDF]

, 2019
Background: Verubecestat, a BACE1 inhibitor that reduces Aβ levels in the cerebrospinal fluid of humans, was not effective in a phase 3 trial (EPOCH) of mild-to-moderate AD and was associated with adverse events.
Aisen, Paul S., Cummings, Jeffrey L., Egan, Michael F., Furtek, Christine, Kost, James, Lines, Christopher, Mahoney, Erin, Michaelson, David, Mukai, Yuki, Stone, Julie, Tariot, Pierre N., Vellas, Bruno, Voss, Tiffini   +12 more
core   +3 more sources

Use of a continuous single lead electrocardiogram analytic to predict patient deterioration requiring rapid response team activation.

PLOS Digital Health
Identifying the onset of patient deterioration is challenging despite the potential to respond to patients earlier with better vital sign monitoring and rapid response team (RRT) activation.
Sooin Lee, Bryce Benson, Ashwin Belle, Richard P Medlin, David Jerkins, Foster Goss, Ashish K Khanna, Michael A DeVita, Kevin R Ward   +8 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Community Perceptions of Valparaiso University [PDF]

, 2011
Community relations is vital to an organization. Valparaiso University relies on the relationships within the community. For example, the university has a Town and Gown Committee representing the community and the university.
Branum, Marie
core   +2 more sources

People with mild cognitive impairment are at increased risk of serious injury

International Journal of Population Data Science, 2018
Introduction Data-linkage studies using administrative hospital data have shown that people with dementia have double the rate of injury-related hospitalisations and poorer health outcomes than those without.
Lara Harvey, Barbara Toson, Henry Brodaty, Brian Draper, Nicole Kochan, Perminder Sachdev, Rebecca Mitchell, Jacqueline Close   +7 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Empirical Study of Privacy Issues Among Social Networking Sites. [PDF]

, 2010
Social media networks are increasing their types of services and the numbers of users are rapidly growing. However, online consumers have expressed concerns about their personal privacy protection and recent news articles have shown many privacy breaches
Kuzma, Joanne
core   +1 more source

Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease [PDF]

, 2013
The aim of the study was to characterize pharmacokinetics of tiotropium solution 5 µg compared to powder 18 µg and assess dose-dependency of tiotropium solution pharmacodynamics in comparison to placebo.
Cornelissen, PJG, Derom, Eric, Disse, B, Hohlfeld, JM, Peterkin, V, Sharma, A, Towse, L, van Noord, JA   +7 more
core   +1 more source

Intergenerational teen pregnancy: a population based cohort study

International Journal of Population Data Science, 2018
Introduction Mothers can influence on a teen’s knowledge and attitude about sexual and reproductive health practices. Prior studies on intergenerational teen pregnancy between mother and daughter were largely limited to livebirths.
Ning Liu, Simone Vigod, Michèle Farrugia, Marcelo Urquia, Joel Ray   +4 more
doaj   +1 more source