Results 31 to 40 of about 326,403 (287)

Trayectorias vitales de jóvenes en contextos de pobreza crítica. Un estudio en Gran San Miguel de Tucumán (Argentina)

open access: yesPoblación & Sociedad, 2020
El presente artículo se centra en jóvenes de áreas de pobreza crítica del aglomerado Gran San Miguel de Tucumán y busca indagar sobre sus trayectorias vitales. Frente a las dificultades que tienen para permanecer en el sistema educativo y las inserciones
Alejandra del Castillo
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Servicios públicos domiciliarios: ¿derechos humanos o productos para la venta? caso Medellín (home utilities: are they human rights or products for sale? the medellin case)

open access: yesEl Ágora USB, 2014
RESUMEN: El presente artículo presenta los resultado de investigación encaminada a demostrar y visibilizar, en la ciudad de Medellín, las múltiples afectaciones a personas por la ausencia de servicios públicos domiciliarios en sus viviendas, aún y la ...
Fabián Alirio Mazo Elorza
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Measuring Vitality [PDF]

open access: yesJournal of the Royal Society of Medicine, 1990
Subjective perceptions of mental and physical energy were measured by the use of visual analogue scales (VAS) over the course of a week in a group of normal volunteers. These variables were found to correlate, highly both with one another and with assessments of vigour and fatigue measured with a standard adjectival format.
C, Wood, M E, Magnello, T, Jewell
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Propiedades psicométricas del Cuestionario de Sucesos Vitales (CSV) en una muestra de adultos ecuatorianos

open access: yesActualidades en Psicología
Objetivo. El objetivo del estudio fue adaptar y validar el Cuestionario de Sucesos Vitales (CSV) en el contexto ecuatoriano. Método. El diseño del estudio fue de tipo instrumental y participaron 417 personas adultas (M = 37.1; DE = 8.67). Resultados.
Jimena B. Agila-Cuji   +1 more
doaj   +1 more source

Enrique García Santo-Tomás, "Signos vitales. Procreación e imagen en la narrativa áurea"

open access: yesStudia Aurea: Revista de Literatura Española y Teoría Literaria del Renacimiento y Siglo de Oro, 2021
Reseña de Enrique García Santo-Tomás, Signos vitales. Procreación e imagen en la narrativa áurea.
Jorge García
doaj   +1 more source

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