Results 41 to 50 of about 37,247 (292)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Signos vitales en pediatría. [PDF]
Los signos vitales son la manifestación externa de funciones vitales básicas tales como la respiración, la circulación y el metabolismo, los cuales pueden ser evaluados en el examen físico y medirse a través de instrumentos simples.
Cobo, Darío, Daza, Paola
core
Objetivo. El objetivo del estudio fue adaptar y validar el Cuestionario de Sucesos Vitales (CSV) en el contexto ecuatoriano. Método. El diseño del estudio fue de tipo instrumental y participaron 417 personas adultas (M = 37.1; DE = 8.67). Resultados.
Jimena B. Agila-Cuji +1 more
doaj +1 more source
Enrique García Santo-Tomás, "Signos vitales. Procreación e imagen en la narrativa áurea"
Reseña de Enrique García Santo-Tomás, Signos vitales. Procreación e imagen en la narrativa áurea.
Jorge García
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Estresores vitales durante la infancia y trastorno de ansiedad: una meta-revisión
Está bien establecido que los estresores vitales durante la infancia, en particular el abuso sexual, se asocian a trastorno de ansiedad y trastorno de estrés postraumático; sin embargo, se cuenta con menor información sobre la relación entre las ...
Edwin Herazo +2 more
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Vital Signsʼ Vital Integration
Vital signs monitoring systems need to pool information from a variety of bedside devices. Add options like portability and multiple parameters, and you can choose the best one for any setting.
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source

