Results 61 to 70 of about 60,694 (274)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Beneficiaries’ satisfaction of the Distintivo Soludable Ecuador Project
MedisurFoundation: excessive exposure to the sun can be harmful to health; it increases the risk of sunburn, causes premature aging and skin cancer.Objectives: to determine the beneficiaries’ knowledge and satisfaction with the policies on photoprotection ...
Angélica Salomé Herrera Molina +5 more
doaj
La alimentación en las distintas etapas vitales
Arbor: Ciencia, Pensamiento y Cultura, 2001 No ...
Rosaura Farré Rovira +1 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
La rebelión de los instintos vitales
Ideas y Valores, 1980 Este texto es la conferencia de Herbert Marcuse el 18 de mayo de 1979 en el 6° coloquio "Römerberg" de Frankfurt. El original alemán apareció en "Psychologie heute", VI, No. 9, Weinheim, Sep. de 1979.
Herbert Marcuse, Guillermo Hoyos (trad.)
doaj
Las voluntades anticipadas (el testamento vital) en el ordenamiento jurídico español
, 2021 Henar Álvarez Cuesta
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Vital Support of Information Technology in India during Novel Coronavirus Disease 2019
, 2023 Shalini Jaiswal, Pooja Singh
openalex +1 more source