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Alloferon Affects the Chemosensitivity of Pancreatic Cancer by Regulating the Expression of SLC6A14

open access: yesBiomedicines, 2022
Pancreatic cancer (PCa), one of the most malignant solid tumors, has a high mortality rate. Although there have been many trials of chemotherapeutic drugs such as gemcitabine, the mortality rates remain significantly higher than for other types of cancer.
Hyejung Jo   +9 more
doaj   +1 more source

Low Iodine Status in a Large Pregnancy Cohort in Ireland

open access: yesProceedings, 2023
Background: Iodine is an essential component of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), which are required for brain development [...]
Lisa Kelliher   +4 more
doaj   +1 more source

Vitamin K content of cheese, yoghurt and meat products in Australia [PDF]

open access: yesFood Chem. 397:133772 (2022), 2022
Vitamin K is vital for normal blood coagulation, and may influence bone, neurological and vascular health. Data on the vitamin K content of Australian foods are limited, preventing estimation of vitamin K intakes in the Australian population. We measured phylloquinone (PK) and menaquinone (MK) -4 to -10 in cheese, yoghurt and meat products (48 ...
arxiv   +1 more source

The Anti-Inflammatory Effect of Aptamin C on House Dust Mite Extract-Induced Inflammation in Keratinocytes via Regulation of IL-22 and GDNF Production

open access: yesAntioxidants, 2021
Atopic dermatitis (AD), a chronic inflammatory skin disease, is characterized by eczemous lesions on the skin that manifest as severe itching and last a long time.
Dahae Lee   +9 more
doaj   +1 more source

The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus

open access: yesEndocrine Regulations, 2021
Objectives. The present study was designed to assess whether apoptosis-related genes as parp-1 and bax could be targets for treatment of diabetes mellitus and whether vitamin D may exert beneficial effects.
Kuchmerovska Tamara   +5 more
doaj   +1 more source

Prebiotic Vitamin B$_3$ Synthesis in Carbonaceous Planetesimals [PDF]

open access: yesChemPlusChem 2023, e202300508, 2023
Aqueous chemistry within carbonaceous planetesimals is promising for synthesizing prebiotic organic matter essential to all life. Meteorites derived from these planetesimals delivered these life building blocks to the early Earth, potentially facilitating the origins of life.
arxiv   +1 more source

Effects of paprika carotenoid supplementation on bone turnover in postmenopausal women: a randomized, double-blind, placebo-controlled, parallel-group comparison study

open access: yesFood & Nutrition Research, 2020
Background: Paprika (Capsicum annuum L.) is a good source of carotenoids, including capsanthin, β-carotene, β-cryptoxanthin, and zeaxanthin. Several epidemiological studies have shown a beneficial association of intake of these carotenoids or their blood
Naofumi Umigai   +3 more
doaj   +1 more source

The Potential of 2-aza-8-Oxohypoxanthine as a Cosmetic Ingredient

open access: yesCosmetics, 2021
In this study, we verified the effects of 2-aza-8-oxohypoxanthine (AOH) on human epidermal cell proliferation by performing DNA microarray analysis. Cell proliferation was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide ...
Hisae Aoshima   +3 more
doaj   +1 more source

Infant Serum and Maternal Milk Vitamin B-12 Are Positively Correlated in Kenyan Infant-Mother Dyads at 1-6 Months Postpartum, Irrespective of Infant Feeding Practice. [PDF]

open access: yes, 2018
BackgroundVitamin B-12 is an essential nutrient required for many functions including DNA synthesis, erythropoiesis, and brain development. If maternal milk vitamin B-12 concentrations are low, infants may face elevated risks of deficiency when ...
Achando, Beryl   +9 more
core   +3 more sources

Clinical Evaluation of Topical Lotion Containing 2-Aza-8-Oxohypoxanthine on Skin Barrier Function against Water Loss

open access: yesCosmetics, 2021
A clinical study was conducted to evaluate the efficacy of 2-aza-8-oxohypoxanthine (AOH) on human skin in a double-blind, placebo-controlled, and split-face comparative trial.
Hisae Aoshima   +3 more
doaj   +1 more source

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