Results 131 to 140 of about 1,458,636 (316)

Associations of single and multiple vitamin levels with pediatric oral mucosal diseases: a cross-sectional study with multi-model analysis

open access: yesFrontiers in Nutrition
BackgroundVitamins play a crucial role in children’s oral health, yet the associations between multiple vitamins and pediatric oral mucosal diseases (OMDs) remain unclear.
Panpan Fang   +9 more
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen   +4 more
wiley   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

open access: yesAdvanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao   +17 more
wiley   +1 more source

Faktor determinan hipertensi pada wanita usia produktif dengan hipertensi di Kota Semarang

open access: yesJurnal Gizi Klinik Indonesia
Determinant factors among hypertensive productive-age women in Semarang Background: Hypertension is a significant risk factor for developing cardiovascular disease, stroke, and kidney disease.
Heni Hendriyani   +2 more
doaj   +1 more source

Vitamin D: vitamin prošlosti, hormon budućnosti

open access: yesLiječnički vjesnik : glasilo Hrvatskoga liječničkog zbora, 2011
Rastuća je spoznaja o brojnim važnim fiziološkim učincima vitamina D u zadnjih desetak godina. Vitamin D regulira funkciju oko 3% ljudskog genoma. S druge strane prevalencija nedostatka vitamina D visoka je u različitim populacijama diljem svijeta uključujući i Hrvatsku. Članak daje prikaz metabolizma vitamina D te današnje spoznaje o učinku vitamina D
Laktašić-Žerjavić, Nadica   +3 more
openaire   +4 more sources

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

open access: yesAdvanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann   +15 more
wiley   +1 more source

Sex-Based Analysis of Health and Micronutrient Status in Austrian Adults Focusing on the Role of Blood Micronutrients in Predicting Blood Lipids and Body Composition

open access: yesDietetics
Sex differences are known to influence both micronutrient metabolism and cardiometabolic health outcomes. However, the extent to which these sex-specific factors interact, particularly in the relationship between micronutrient status and cardiometabolic ...
Mohamad Motevalli   +7 more
doaj   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

open access: yesAdvanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil   +7 more
wiley   +1 more source

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