Results 161 to 170 of about 2,020,358 (433)

Genomics-guided molecular maps of coronavirus targets in human cells: a path toward the repurposing of existing drugs to mitigate the pandemic [PDF]

open access: yesarXiv, 2020
Human genes required for SARS-CoV-2 entry into human cells, ACE2 and FURIN, were employed as baits to build genomics-guided maps of up-stream regulatory elements, their expression and functions in human body, including pathophysiologically-relevant cell types.
arxiv  

Artificially Weaved Textile‐like Surface Micromachined Graphene‐Polymer Flexible Bioelectrodes

open access: yesAdvanced Materials Technologies, EarlyView.
This study reports on the engineering of microscale textured surfaces of SU‐8/PMMA polymer composites much like a “weft‐warp” pattern to resemble “artificially‐weaved” textiles. These microstructured surfaces enable conformal layering of functional reduced graphene oxide (rGO), all‐in‐all offering favorable features including remarkable self ...
Seba Nur Alhasan   +6 more
wiley   +1 more source

The effect of feeding adequate or deficient vitamin B6 or folic acid to breeders on methionine metabolism in 18-day-old chick embryos

open access: yesPoultry Science, 2021
Three isotopic tracers ([2,3,3-2H3]-L-serine, [2H11]-L-betaine, and [1-13C]-L-methionine) were administered by amnion injection into 18-day-old chick embryos to investigate the kinetics of methionine metabolism.
J. Lu   +5 more
doaj  

What Is the Role of Dietary Inflammation in Severe Mental Illness? A Review of Observational and Experimental Findings

open access: yesFrontiers in Psychiatry, 2019
Severe mental illnesses (SMI), including major depressive disorder, bipolar disorder, and schizophrenia, are associated with increased inflammation.
Joseph Firth   +17 more
doaj   +1 more source

Development of a Machine Learning Model and Mobile Application to Aid in Predicting Dosage of Vitamin K Antagonists Among Indian Patients [PDF]

open access: yesarXiv, 2020
Patients who undergo mechanical heart valve replacements or have conditions like Atrial Fibrillation have to take Vitamin K Antagonists (VKA) drugs to prevent coagulation of blood. These drugs have narrow therapeutic range and need to be very closely monitored due to life threatening side effects.
arxiv  

Enzymatic Asymmetric Synthesis of All Stereoisomers of Aliphatic, Vicinal Diols in Conventional and Non‐Conventional Media

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract Chiral, vicinal diols are of high interest for academic research and industrial applications. For synthesizing chiral diols, enzymes are important catalysts due to their high selectivity and ability to work under tolerable temperature and no pressure.
Maria Nicolas   +8 more
wiley   +1 more source

Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. [PDF]

open access: yes, 2015
Vitamin A has biological functions as diverse as sensing light for vision, regulating stem cell differentiation, maintaining epithelial integrity, promoting immune competency, regulating learning and memory, and acting as a key developmental morphogen ...
Kassai, Miki   +4 more
core   +2 more sources

Overview of general physiologic features and functions of vitamin D.

open access: yesAmerican Journal of Clinical Nutrition, 2004
Vitamin D3 is a prohormone produced in skin through ultraviolet irradiation of 7-dehydrocholesterol. It is biologically inert and must be metabolized to 25-hydroxyvitamin D3 in the liver and then to 1alpha,25-dihydroxyvitamin D3 in the kidney before ...
H. DeLuca
semanticscholar   +1 more source

Ammonia Dynamics in the Human Body: Insights in Biomedical Sensing Technologies

open access: yesAdvanced Sensor Research, EarlyView.
Ammonia (NH3) is a significant biomarker in diagnostics, affecting the respiratory system, stomach, liver, kidneys, bladder, and gastrointestinal tract. NH3 detection, using sensors, has the potential to improve medical diagnosis. This review examines recent advancements in NH3 sensing technologies and explores future research directions, including ...
Annelot Nijkoops   +8 more
wiley   +1 more source

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