Genomics-guided molecular maps of coronavirus targets in human cells: a path toward the repurposing of existing drugs to mitigate the pandemic [PDF]
Human genes required for SARS-CoV-2 entry into human cells, ACE2 and FURIN, were employed as baits to build genomics-guided maps of up-stream regulatory elements, their expression and functions in human body, including pathophysiologically-relevant cell types.
arxiv
An investigation of vitamin D metabolism in kiwi (Apteryx mantelli), tuatara (Sphenodon punctatus) and New Zealand sea lion (Phocarctos hookeri) and the relationship of vitamin D metabolism with their life history characteristics : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Studies at Massey University, Turitea, Palmerston North, New Zealand [PDF]
Vitamin D, a fat-soluble vitamin, has a wide range of functions in vertebrates. The aim of the study was to determine if the evolutionary history of different animal species affects their predominant route of vitamin D metabolism.
Kale, Madhumita Sanjay
core
Artificially Weaved Textile‐like Surface Micromachined Graphene‐Polymer Flexible Bioelectrodes
This study reports on the engineering of microscale textured surfaces of SU‐8/PMMA polymer composites much like a “weft‐warp” pattern to resemble “artificially‐weaved” textiles. These microstructured surfaces enable conformal layering of functional reduced graphene oxide (rGO), all‐in‐all offering favorable features including remarkable self ...
Seba Nur Alhasan+6 more
wiley +1 more source
Three isotopic tracers ([2,3,3-2H3]-L-serine, [2H11]-L-betaine, and [1-13C]-L-methionine) were administered by amnion injection into 18-day-old chick embryos to investigate the kinetics of methionine metabolism.
J. Lu+5 more
doaj
Severe mental illnesses (SMI), including major depressive disorder, bipolar disorder, and schizophrenia, are associated with increased inflammation.
Joseph Firth+17 more
doaj +1 more source
Development of a Machine Learning Model and Mobile Application to Aid in Predicting Dosage of Vitamin K Antagonists Among Indian Patients [PDF]
Patients who undergo mechanical heart valve replacements or have conditions like Atrial Fibrillation have to take Vitamin K Antagonists (VKA) drugs to prevent coagulation of blood. These drugs have narrow therapeutic range and need to be very closely monitored due to life threatening side effects.
arxiv
Abstract Chiral, vicinal diols are of high interest for academic research and industrial applications. For synthesizing chiral diols, enzymes are important catalysts due to their high selectivity and ability to work under tolerable temperature and no pressure.
Maria Nicolas+8 more
wiley +1 more source
Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. [PDF]
Vitamin A has biological functions as diverse as sensing light for vision, regulating stem cell differentiation, maintaining epithelial integrity, promoting immune competency, regulating learning and memory, and acting as a key developmental morphogen ...
Kassai, Miki+4 more
core +2 more sources
Overview of general physiologic features and functions of vitamin D.
Vitamin D3 is a prohormone produced in skin through ultraviolet irradiation of 7-dehydrocholesterol. It is biologically inert and must be metabolized to 25-hydroxyvitamin D3 in the liver and then to 1alpha,25-dihydroxyvitamin D3 in the kidney before ...
H. DeLuca
semanticscholar +1 more source
Ammonia Dynamics in the Human Body: Insights in Biomedical Sensing Technologies
Ammonia (NH3) is a significant biomarker in diagnostics, affecting the respiratory system, stomach, liver, kidneys, bladder, and gastrointestinal tract. NH3 detection, using sensors, has the potential to improve medical diagnosis. This review examines recent advancements in NH3 sensing technologies and explores future research directions, including ...
Annelot Nijkoops+8 more
wiley +1 more source