Results 61 to 70 of about 243,218 (312)

The Double-Edged Sword of Vitamin A: Function and Toxicity

Quality in Sport
Introduction: This article investigates the essential functions and health risks of vitamin A, focusing on its metabolic pathways, dietary origins, daily requirements, the clinical consequences of deficiency and the harmful effects of overdose ...
Paulina Grzeszczuk, Magdalena Jabłonowska   +1 more
doaj   +1 more source

Vitamin E deficiency [PDF]

BMJ, 1995
EDITOR,—Minerva suggests that vitamin E is a vitamin without a deficiency disease.1 This is incorrect. …
openaire   +2 more sources

Human Gut Bacteria and Lipidic Nanoparticles: Particle Composition Predicts Structural Transformation and Bacterial Biocompatibility

Advanced Functional Materials, EarlyView.
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell, Emily L. Gulliver, Livia Salvati Manni, Frithjof Herb, Caitlin Welsh, Samuel C. Forster, Andrew J. Clulow, Wye‐Khay Fong   +7 more
wiley   +1 more source

Low vitamin D status adversely affects bone health parameters in adolescents

, 2008
Background: The effects of subclinical vitamin D deficiency on bone mineral density (BMD) and bone turnover in adolescents, especially in boys, are unclear.Objective: We aimed to investigate the relations of different stages of vitamin D status and BMD ...
Cashman, Kevin D, Tom R Hill, Robson, Paula J, Kiely, Mairead, Wallace, Julie MW, Werner Dubitzky, Flynn, Albert, Dubitzky, Werner, Kevin D Cashman, Liam Murray, Paula J Robson, Julie MW Wallace, Colin A Boreham, JJ Strain, Cotter, Alice A, Albert Flynn, Mairead Kiely, Strain, J J, Boreham, Colin A, Hill, Tom R, Murray, Liam, Alice A Cotter   +21 more
core   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Micronutrient malnutrition and wasting in adults with pulmonary tuberculosis with and without HIV co-infection in Malawi. [PDF]

, 2004
BACKGROUND: Wasting and micronutrient malnutrition have not been well characterized in adults with pulmonary tuberculosis. We hypothesized that micronutrient malnutrition is associated with wasting and higher plasma human immunodeficiency virus (HIV ...
Johnny J Kumwenda, Tamara D Clark, Richard D Semba, Harries Anthony D, Zijlstra, Ed E, Clark Tamara D, Taha Taha E, Taha, Taha E, Kumwenda, Johnny J, Semba Richard D, Anthony D Harries, Kumwenda Johnny J, Zijlstra Ed E, Harries, Anthony D, Monique van Lettow, Taha E Taha, Clark, Tamara D, van Lettow Monique, van Lettow, Monique, Ed E Zijlstra, Semba, Richard D   +20 more
core   +1 more source

Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology Unit

International Journal of Endocrinology, 2013
Aims. Kidney disease was found to be a major risk factor for vitamin D deficiency in a population study of patients hospitalized. The aims of the study were to describe the prevalence of vitamin D deficiency inpatients and outpatients in a nephrology ...
Recep Bentli, Hulya Taskapan, Halil Toktaş, Ozkan Ulutas, Adnan Ozkahraman, Melda Comert   +5 more
doaj   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Hypomagnesemia and vitamin D deficiency complicating bisphosphonate induced hypocalcaemia [PDF]

, 2012
Zolendronic acid is a potent bisphosphonate that is used to treat patients with metastatic cancer by reducing bone pain and preventing skeletal complications of bone metastasis.
Bigeni, Josephine, Vella, Antoine
core  

Clinical implications of vitamin D deficiency

, 2015
Vitamin D deficiency is a common medical problem worldwide and its prevalence rises along with latitude, obesity, sedentary lifestyle, limited sunlight exposure and aging.
Ewa Woźniakowska, Monika Lenart-Lipińska, Beata Matyjaszek-Matuszek   +2 more
core   +1 more source