Results 41 to 50 of about 13,874,644 (302)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effect of Ultraviolet Irradiation on Vitamin D in Commonly Consumed Mushrooms in Thailand

Foods, 2023
This study examined the effect and stability of ultraviolet B (UV-B) irradiation and subsequent cooking on vitamin D content in commonly consumed mushrooms in Thailand.
Kunchit Judprasong, Sochannet Chheng, Chanika Chimkerd, Sitima Jittinandana, Nattapol Tangsuphoom, Piyanut Sridonpai   +5 more
doaj   +1 more source

Crosstalk between vitamin B and immunity

, 2015
Vitamin B1 (Thiamin) is considered to be the oldest vitamin ann in 1936 was determined its chemical stucture and were able to syhtesize this vitamin.
Cerulli, G., Pantalone, A., Speziali, Andrea, S.K. Kritas (3137151), E. Spinas (3137154), SPINAS, ENRICO, A. Caraffa (3137175), Pandolfi, Federica, R. Saggini (3137187), Saggini, A., Kritas, S. K., P. Antinolfi (3137142), Tei, Matteo Maria, A. Saggini (3137163), G. Cerulli (3137172), Cerulli, Giuliano Giorgio, F. Pandolfi (3137169), Pandolfi, F., M. Tei (3137178), A. Speziali (3137190), Pio Conti (3137121), A. Frydas (3137181), Tei, M., Conti, P., Frydas, A., Antinolfi, P., Speziali, A., Caraffa, A., A. Pantalone (3137184), Saggini, R.   +29 more
core   +1 more source

Month of birth, vitamin D and risk of immune mediated disease: a case control study [PDF]

, 2012
: BACKGROUND: A season of birth effect in immune-mediated diseases (ID) such as multiple sclerosis and type 1 diabetes has been consistently reported. We aimed to investigate whether season of birth influences the risk of rheumatoid arthritis, Crohn's ...
Chaplin, G, Giovannoni Gavin, Giulio Disanto, Gavin Giovannoni, Morahan, JM, Ramagopalan, SV, Chaplin George, Hyppönen Elina, Ebers George C, Hyppoenen, E, Elina Hyppönen, George C Ebers, Disanto Giulio, Sreeram V Ramagopalan, Ebers, GC, George Chaplin, Ramagopalan Sreeram V, Julia M Morahan, Morahan Julia M, Giovannoni, G, Disanto, G, Hypponen, E   +21 more
core   +2 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Involvement of Spermidine in the Reduced Lifespan of Caenorhabditis elegans During Vitamin B₁₂ Deficiency

Metabolites, 2019
Vitamin B12 deficiency leads to various symptoms such as neuropathy, growth retardation, and infertility. Vitamin B12 functions as a coenzyme for two enzymes involved in amino acid metabolisms.
Tomohiro Bito, Naho Okamoto, Kenji Otsuka, Yukinori Yabuta, Jiro Arima, Tsuyoshi Kawano, Fumio Watanabe   +6 more
doaj   +1 more source

Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. [PDF]

PLoS ONE, 2016
Normal or high serum vitamin B-12 levels can sometimes be seen in a B-12 deficient state, and can therefore be misleading. High levels of Methymalonic Acid (MMA) and Homocysteine (HC) have been identified as better indicators of B-12 deficiency than the ...
Pankaj Vashi, Persis Edwin, Brenten Popiel, Carolyn Lammersfeld, Digant Gupta   +4 more
doaj   +1 more source

DHCR7 mutations linked to higher vitamin D status allowed early human migration to Northern latitudes [PDF]

, 2013
Vitamin D is essential for a wide range of physiological processes including immune function and calcium homeostasis. Recent investigations have identified candidate genes which are strongly linked to concentrations of 25-hydroxyvitamin D. Since there is
Robert Walton, Hyppönen, E., Walton, Robert T., Kuan, V, Valerie Kuan, Griffiths, C. J., Martineau, AR, Hyppoenen, E, Hyppönen, E, Elina Hyppönen, Martineau, A. R., Walton, R, Griffiths, CJ, Adrian R Martineau, Kuan, V., Chris J Griffiths   +15 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Vitamin D supplementation in patients with diabetes mellitus type 2 on different therapeutic regimens : a one-year prospective study [PDF]

, 2013
Background Little or no research has determined the effect of vitamin D3 supplementation in conjunction with pharmacological and non-pharmacological approaches in the diabetes mellitus type 2 (DMT2) patients. The objective of this study was to determine
Majed S Alokail, Al-Othman, Abdulaziz, Osama Moharram, Yousef Al-Saleh, Shaun B Sabico, Chrousos, George P., Kumar, Sudhesh, Sabico, Shaun, Abdulaziz Al-Othman, Nasser M Al-Daghri, Sudhesh Kumar, George P Chrousos, Alokail, Majed S., Al-Daghri, Nasser M., Al-Saleh, Yousef, Moharram, Osama, Alkharfy, Khalid M., Khalid M Alkharfy   +17 more
core   +1 more source