Results 61 to 70 of about 13,874,644 (302)

MAVIDOS maternal vitamin D osteoporosis study: study protocol for a randomized controlled trial. The MAVIDOS Study Group [PDF]

, 2012
: MAVIDOS is a randomised, double-blind, placebo-controlled trial (ISRCTN82927713, registered 2008 Apr 11), funded by Arthritis Research UK, MRC, Bupa Foundation and NIHR.BACKGROUND:Osteoporosis is a major public health problem as a result of associated ...
Gandhi Saurabh V, Javaid, M.K., Schoenmakers, I., Nicholas Bishop, Fraser, R, Schoenmakers, I, Gandhi, Saurabh V., Ann Prentice, Nicholas C Harvey, Prentice, A., Prentice, A, Cooper Cyrus, Cyrus Cooper, Schoenmakers, Inez, Harvey, NC, Bishop, N., Inez Schoenmakers, Harvey, N.C., Kennedy, S., Schoenmakers Inez, Kassim Javaid, Prentice, Ann, Robert Fraser, Kennedy, Stephen, Prentice Ann, Papageorghiou, A.T., Harvey, Nicholas C., Fraser Robert, Fraser, Robert, Stephen Kennedy, Cooper, Cyrus, Papageorghiou, Aris T., Gandhi, SV, Javaid Kassim, Fraser, R., Kennedy, S, Papageorghiou Aris T, Saurabh V Gandhi, Bishop Nicholas, Javaid, Kassim, Gandhi, S.V., Javaid, K., Bishop, N, Kennedy Stephen, Cooper, C., Javaid, K, Aris T Papageorghiou, Harvey Nicholas C, Cooper, C, Papageorghiou, AT, Bishop, Nicholas   +50 more
core   +4 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Vitamin B Deficiency Does not Affect the Liver Concentrations of the Other Seven Kinds of B-Group Vitamins in Rats

Nutrition and Metabolic Insights, 2013
We aimed to determine the effects of vitamin B 1 deficiency on vitamin contents of urine, liver, and blood. In the current study, rats were divided into 3 groups (n = 5, each group): the first was freely fed a complete diet (ad lib-fed control group ...
Katsumi Shibata, Atsushi Shimizu, Tsutomu Fukuwatari   +2 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Beyond deficiency:Potential benefits of increased intakesof vitamin K for bone and vascular health [PDF]

, 2004
Vitamin K is wellknown for its role in the synthesisof a number of blood coagulationfactors.During recent years vitaminK-dependent proteins werediscovered to be of vital importancefor bone and vascular health.Recommendations for dietary vitaminK intake ...
Vermeer, C, Weber, P, Zittermann, A, Shearer, M, Szulc, P, Walter, P, Stocklin, E, Bolton-Smith, C, Rambeck, W, Hodges, S   +9 more
core  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

The Role of Vitamin B in the Management and Optimization of Treatment in Patients With Degenerative Cervical Myelopathy

Global Spine Journal, 2019
Study Design: Narrative review. Objectives: To discuss the relationship between degenerative cervical myelopathy (DCM) and vitamin B 12 deficiency. Specifically, it is the aim to outline the rational for future research into assessment and therapeutic ...
Aria Nouri MD, MSc, Kishan Patel BA, Julio Montejo BA, Rani Nasser MD, David A. Gimbel MD, Daniel M. Sciubba MD, Joseph S. Cheng MD, MS, FAANS, FACS   +6 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Low-normal vitamin B

Blood Red Cells & Iron
: Vitamin B 12 deficiency is a well-known cause of macrocytic anemia. Low-normal levels of vitamin B 12 are also often believed to cause macrocytic anemia, but data to support this are lacking.
Thomas F. Fusillo, Angela Liu, Daniel I. Nathan, Alfred Burger   +3 more
doaj   +1 more source

Efficacy of Supplementation with B Vitamins for Stroke Prevention: A Network Meta-Analysis of Randomized Controlled Trials.

PLoS ONE, 2015
BackgroundSupplementation with B vitamins for stroke prevention has been evaluated over the years, but which combination of B vitamins is optimal for stroke prevention is unclear.
Hongli Dong, Fuhua Pi, Zan Ding, Wei Chen, Shaojie Pang, Wenya Dong, Qingying Zhang   +6 more
doaj   +1 more source