Results 81 to 90 of about 469,719 (256)
Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
Advanced Science, EarlyView.A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang +12 more
wiley +1 more source
Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
Advanced Science, EarlyView.ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
Genetic features of sensitivity to vitamin D and prevalence of vitamin D deficiency among outpatients [PDF]
РМЖ. Мать и дитя, 2018 Genetic features of sensitivity to vitamin D and prevalence of vitamin D deficiency among outpatients A.Yu. Poluektova1, E.Yu. Martynova2, I.R. Fatkhutdinov3, T.Yu. Demidova3, Yu.E.
A.Yu. Poluektova +4 more
doaj
Advanced Science, EarlyView.An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong +14 more
wiley +1 more source
B vitamin in walnuts: Studies of components of vitamin B complex in walnut meats extended
California Agriculture, 1954 Three varieties of walnuts–Payne, Placentia, and Franquette–Juglans regia on J. negri rootstock–were analyzed for their content of pantothenic acid, folie acid, and vitamin B6 in an extension of previous studies of the vitamins thiamine, riboflavin, and ...
A Hall, P Wheeler, A Thielen, A Morgan
doaj
Advanced Science, EarlyView.NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider +14 more
wiley +1 more source