Results 301 to 310 of about 821,703 (378)

Efficacy of diabetes‐specific partial meal replacement on glycemic and weight control in type 2 diabetes: A randomized controlled trial

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4167-4180, August 2025.
Abstract Aims To evaluate the efficacy of a diabetes‐specific formula (DSF)‐based partial meal replacement (PMR) in improving glycemic control, weight, and underlying hormonal changes among participants with type 2 diabetes and overweight or obesity compared to dietary consultation.
Lew Leong Chen, Noorlaili Mohd Tohit, Arimi Fitri Mat Ludin, Zahara Abdul Manaf, Alicia Wong, Kwan Lee Kuan, Han Wan Chien, Suzana Shahar   +7 more
wiley   +1 more source

Benfotiamine, a Lipid-Soluble Derivative of Vitamin B₁, Ameliorates the Carbohydrate Overload-Induced Mitochondrial Dysfunction in Fish <i>Megalobrama amblycephala</i> by Triggering the ULK1-Mediated Mitophagy. [PDF]

Aquac Nutr
Zhang L, He C, Liu Z, Jiang G, Liu W, Zhang D, Li X.   +6 more
europepmc   +1 more source

Pathogenesis, Non‐Invasive Assessments and Treatment of Hepatic Fibrosis in Autoimmune Liver Diseases

Liver International, Volume 45, Issue 8, August 2025.
ABSTRACT Background and Aims Autoimmune liver diseases (AILD), including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), can lead to progressive liver fibrosis, development of cirrhosis, decompensation, hepatocellular carcinoma (HCC), and need for liver transplantation (LT).
Ellina Lytvyak, Gideon Hirschfield, Devika Shreekumar, Yu Jun Wong, Aldo J. Montano‐Loza   +4 more
wiley   +1 more source

Defective lymphatic vasculature in obesity

Obesity Reviews, Volume 26, Issue 8, August 2025.
Summary Lymphedema is an important, and often underdiagnosed complication of obesity and is likely due to acquired defects in the lymphatic vasculature. Study of diet‐induced obesity animal models have indicated defective lymphatic vasculatures might extend to other anatomical sites, especially visceral depots.
Jingjing Zhu, John P. H. Wilding, Ji Hu
wiley   +1 more source

Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with post-COVID-19-syndrome (PreVitaCOV) - protocol of a randomised, double-blind, placebo-controlled multicentre trial in primary care (phase IIIb). [PDF]

BMC Infect Dis
Tengelmann C, Joos S, Kaußner Y, Malzahn U, Lunden L, Klug A, Häusler KG, Escales C, Maetzler W, Hügen K, Zolk O, Heuschmann PU, Förster C, Kaduszkiewicz H, Gágyor I.   +14 more
europepmc   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, Volume 8, Issue 7, July 2025.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Microbiome Single Cell Atlases Generated with a Commercial Instrument

Advanced Science, Volume 12, Issue 27, July 17, 2025.
Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Xiangpeng Li, Linfeng Xu, Benjamin Demaree, Cecilia Noecker, Jordan E. Bisanz, Daniel W. Weisgerber, Cyrus Modavi, Peter J. Turnbaugh, Adam R. Abate   +8 more
wiley   +1 more source

L‐quebrachitol Modulates the Anti‐convulsant Effects of Carbamazepine Possibly Through Voltage‐gated Sodium Channel Blocking Mechanism in Chicks: In Vivo and In Silico Studies

Brain and Behavior, Volume 15, Issue 7, July 2025.
L‐quebrachitol exhibited significant anticonvulsant effects in PTZ‐induced seizures in chicks, likely through voltage‐gated sodium channel inhibition. In vivo and in silico analyses suggest LQB may synergize with carbamazepine, offering a potential new therapeutic approach for epilepsy management. ABSTRACT Introduction L‐Quebrachitol (LQB), a naturally
Asifa Asrafi, Mohammad Aslam, Ali G. Alkhathami, Md. Sakib Hossain, Imam Hossen Rakib, Md. Sakib Al Hasan, Feroz Khan Nun, Md. Faisal Amin, Muhammad Torequl Islam   +8 more
wiley   +1 more source