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Effects of Vitamin B12 deficiency on hematological parameters
Aims: Vitamin B12 deficiency causes an increase in homocysteine levels which is associated with inflammatory conditions. Mean platelet volume (MPV) and red cell distribution width (RDW) are also associated with inflammation.
GÜLALİ AKTAŞ+5 more
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2022
Photoreceptor proteins enable living organisms to sense light and transduce this signal into biochemical outputs to elicit appropriate cellular responses. Their light sensing is typically mediated by covalently or noncovalently bound molecules called chromophores, which absorb light of specific wavelengths and modulate protein structure and biological ...
Padmanabhan, Subramanian+4 more
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Photoreceptor proteins enable living organisms to sense light and transduce this signal into biochemical outputs to elicit appropriate cellular responses. Their light sensing is typically mediated by covalently or noncovalently bound molecules called chromophores, which absorb light of specific wavelengths and modulate protein structure and biological ...
Padmanabhan, Subramanian+4 more
openaire +3 more sources
Nature Reviews Disease Primers, 2017
Vitamin B12 (B12; also known as cobalamin) is a B vitamin that has an important role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial metabolism. Clinical B12 deficiency with classic haematological and neurological manifestations is relatively uncommon.
Green, Ralph+11 more
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Vitamin B12 (B12; also known as cobalamin) is a B vitamin that has an important role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial metabolism. Clinical B12 deficiency with classic haematological and neurological manifestations is relatively uncommon.
Green, Ralph+11 more
openaire +5 more sources
Biochimica et Biophysica Acta, 1950
Abstract 1. 1. In mildly acid solutions, kept in the dark, the spectrum of vitamin B 12 remains unchanged; on exposure to light, vitamin B 12b is rapidly formed. 2. 2. The spectrum of an irradiated solution ( pH ≧ 4 ), subsequently kept in the dark, shows a slow reversal to that of vitamin B 12 . 3. 3.
W. L. C. Veer+3 more
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Abstract 1. 1. In mildly acid solutions, kept in the dark, the spectrum of vitamin B 12 remains unchanged; on exposure to light, vitamin B 12b is rapidly formed. 2. 2. The spectrum of an irradiated solution ( pH ≧ 4 ), subsequently kept in the dark, shows a slow reversal to that of vitamin B 12 . 3. 3.
W. L. C. Veer+3 more
openaire +3 more sources
BMJ, 2014
#### Summary points Vitamin B12 is an essential cofactor that is integral to methylation processes important in reactions related to DNA and cell metabolism, thus a deficiency may lead to disruption of DNA and cell metabolism and thus have serious clinical consequences.1 Intracellular conversion of vitamin B12 to two active coenzymes ...
Susan Robinson+2 more
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#### Summary points Vitamin B12 is an essential cofactor that is integral to methylation processes important in reactions related to DNA and cell metabolism, thus a deficiency may lead to disruption of DNA and cell metabolism and thus have serious clinical consequences.1 Intracellular conversion of vitamin B12 to two active coenzymes ...
Susan Robinson+2 more
openaire +3 more sources