Results 171 to 180 of about 119,689 (246)

A 15‐year population‐based study on incidence and vaccination coverage in pediatric inflammatory bowel disease in Italy

Pediatric Investigation, EarlyView.
Increasing incidence of pediatric inflammatory bowel disease (IBD) and suboptimal vaccination coverage in Apulia, Italy (2009–2023). A total of 1044 incident cases of paediatric IBD were identified in the period 2009–2023 in Apulia, Italy, giving an average annual standardized incidence rate of 12.7/100 000. A significant increase in incidence occurred
Francesca Fortunato, Angelo Campanozzi, Michele Di Toma, Alessandra Marinari, Domenico Martinelli   +4 more
wiley   +1 more source

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper, Alyssa Powers, Kevin P. Battaile, Al‐Walid Mohsen, David K. Johnson, Scott Lovell, Lina Ghaloul‐Gonzalez   +6 more
wiley   +1 more source

Silibinin‐driven microbial and metabolic reprogramming restores CD4+ T cell immunity in HIV immunological nonresponders

VIEW, EarlyView.
Despite efficacious antiretroviral therapy, 10%–40% of HIV‐infected individuals exhibit inadequate immune reconstitution due to persistent inflammatory activation and NAD+ metabolic dysregulation—a critical cofactor in cellular bioenergetics. We administered silibinin to 53 HIV immunological non‐responders and elucidated its mechanism through selective
Wenli Liu, Minghui An, Qi Wang, Yuxin Shang, Shuyao Zang, Haibo Ding, Shuai Fu, Yun Liu, Xue Dong, Xiao Yang, Jinna Dai, Xiaoxu Han, Yingchun Xu, Hong Shang   +13 more
wiley   +1 more source

Efficacy and Safety of the Combination of Superoxide Dismutase, Alpha Lipoic Acid, Vitamin B12, and Carnitine for 12 Months in Patients with Diabetic Neuropathy [PDF]

, 2020
Triantafyllos Didangelos, Eleni Karlafti, Evangelia Kotzakioulafi, Zisis Kontoninas, Charalampos Margaritidis, Parthena Giannoulaki, Kοnstantinos Kantartzis   +6 more
openalex   +1 more source

Dropped jaw as a feature of suspected nutritional encephalopathy in a cat

Veterinary Record Case Reports, EarlyView.
Abstract A 3‐year‐1‐month‐old female neutered domestic shorthair cat was presented for reluctance to jump over 3 months. Neurological and orthopaedic examinations, laboratory tests and cerebrospinal fluid analysis were unremarkable. Magnetic resonance imaging revealed mild bilateral symmetrical intra‐axial changes in the caudal brainstem.
Eleftheria Skovola, Oliver Williams, Serena Maini, Abbe Crawford   +3 more
wiley   +1 more source

Oral versus intramuscular administration of vitamin B12 for the treatment of patients with vitamin B12 deficiency: a pragmatic, randomised, multicentre, non-inferiority clinical trial undertaken in the primary healthcare setting (Project OB12) [PDF]

, 2012
Teresa Sanz‐Cuesta, Paloma González-Escobar, Rosario Riesgo-Fuertes, Sofía Garrido-Elustondo, Isabel del Cura-González, Jesús Martín‐Fernández, Esperanza Escortell‐Mayor, Francisco Rodríguez Salvanés, Marta García‐Solano, R. González, María Ángeles Martín-de la Sierra-San Agustín, Carmen Olmedo-Lucerón, María Luisa Sevillano Palmero, Carmen Mateo-Ruiz, Beatriz Medina-Bustillo, Antonio Valdivia-Pérez, Francisca García-de Blas-González, José Enrique Mariño-Suárez, Ricardo Rodríguez-Barrientos, Gloria Ariza-Cardiel, Luisa Cabello-Ballesteros, Elena Polentinos-Castro, Milagros Rico‐Blázquez, Ma Teresa Rodríguez-Monje, Sonia Soto-Díaz, Susana Martín‐Iglesias, Ramón Rodríguez‐González, Irene Bretón Lesmes, María Teófila Vicente-Herrero, Jesús Sánchez-Díaz, Tomás Gómez‐Gascón, M. Canela, Ángel Asúnsolo   +32 more
openalex   +1 more source

Nutritional approach in a growing Jack Russell terrier with gall bladder agenesis

Veterinary Record Case Reports, EarlyView.
Abstract An asymptomatic male Jack Russell terrier diagnosed at the age of 18 weeks with congenital gall bladder agenesis, confirmed by computed tomography scan, after finding abnormally high values for liver enzymes in a routine blood count. Treatment with liver‐protective agents S‐adenosylmethionine and ursodeoxycholic acid was initiated. At 6 months
Tamara Seghers, Matthias Dennler, Brigitta Wichert, Annette Liesegang   +3 more
wiley   +1 more source

Study of Serum Vitamin B12 Level in Population Consuming Tobacco in Various Forms as Compared to Non-Tobacco Users

National Journal of Community Medicine, 2017
 Introduction: Tobacco consumption is risk factor for so many diseases. Experimental and clinical evidence both suggest that there is some connection between metabolism of vitamin B12 and that of cyanide.
Jyoti H Vora, Harsh N Oza
doaj  

STUDIES ON THE RELATIONSHIPS OF VITAMIN B12, FOLIC ACID, THYMINE, URACIL, AND METHYL GROUP DONORS IN PERSONS WITH PERNICIOUS ANEMIA AND RELATED MEGALOBLASTIC ANEMIAS [PDF]

, 1950
Richard W. Vilter, Daniel L. Horrigan, John F. Mueller, Thomas Jarrold, CARL F. VILTER, V. Hawkins, Arthur J. Seaman   +6 more
openalex   +1 more source

Analysis of Heme Using a Combination of Total Reflection X‐Ray Fluorescence Analysis and Solid‐Phase Extraction

X-Ray Spectrometry, EarlyView.
ABSTRACT In this study, a method to analyze iron originating from heme using a combination of total reflection X‐ray fluorescence (TXRF) analysis and solid‐phase extraction is presented. In this method, heme in a sample solution was collected on a reverse‐phase solid‐phase extraction column filled with octadecyl bonded silica, and then the collected ...
Haruka Hoshi, Shinsuke Kunimura
wiley   +1 more source