Results 151 to 160 of about 424,620 (246)

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Reduced Circulating Regulatory T Cells in Autoimmune and Chronic Idiopathic Neutropenia of Childhood: An Observational Study of Clinical and Laboratory Associations

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Objectives To investigate circulating regulatory T cells (Tregs) in children with autoimmune neutropenia (AIN) and chronic idiopathic neutropenia (CIN) and evaluate their associations with clinical and laboratory features of neutropenia. Methods Plasma and Peripheral Blood Mononuclear Cells (PBMCs) were collected from 69 participants.
Konstantina Toutoudaki   +12 more
wiley   +1 more source

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

open access: yesThe FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva   +5 more
wiley   +1 more source

From OCD Symptoms to Sleep Disorders: The Crucial Role of Vitamin B12

open access: yes
Shaoxia Wang,1– 3 Xiang Zhang,1 Yanru Ding,1 Yanrong Wang,2,4 Chujun Wu,2,4 Shihao Lu,1,2 Jianqun Fang2,4 1School of First Clinical, Ningxia Medical University, Yinchuan, Ningxia, 750004, People’s Republic of China; 2Institute of Medical Sciences ...
Ding Y   +6 more
core  

Human APOBEC3G suppresses homologous recombination and LIG4‐independent end joining in DNA double‐strand break repair

open access: yesThe FEBS Journal, EarlyView.
Chromosomal DNA double‐strand breaks (DSBs) are repaired by homologous recombination and nonhomologous end joining (NHEJ). Recent work has additionally established theta‐mediated end‐joining (TMEJ) as a mechanism for DSB joining. Cells lacking NHEJ and TMEJ can repair DSBs in a homology‐dependent manner.
Shinta Saito   +6 more
wiley   +1 more source

Skin Hyperpigmentation: An Under-Recognized Dermatological Clue to Vitamin B12 Deficiency. [PDF]

open access: yesClin Case Rep
Mathur M   +5 more
europepmc   +1 more source

Ulceronecrotic Plaques, Patchy Scalp Alopecia and Visual Disturbance in a 46‐Year‐Old Man

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT A 46‐year‐old incarcerated man with chronic hepatitis C infection and intravenous drug use presented with a rapidly progressive pruritic eruption involving the scalp, trunk, and limbs, accompanied by patchy scalp alopecia and bilateral panuveitis.
Alex Majri   +3 more
wiley   +1 more source

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