Results 201 to 210 of about 387,407 (285)

Efficacy and Safety of Ultra‐Low Starting Dose Febuxostat Titration in Male Patients With Primary Gout

International Journal of Rheumatic Diseases, Volume 29, Issue 9, September 2026.
ABSTRACT Background Since gout is a common metabolic arthritis caused by urate crystal deposition, urate‐lowering therapy (ULT) is clearly indicated, but the initiation of ULT frequently causes paradoxical acute flares that in turn impair patient adherence.
Sun Huizhen, Li Yadi, Guo Lin, Sun Rui, Guo Xuemei, Li Ping   +5 more
wiley   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6? [PDF]

Oral Dis
Obermeier KT, Hildebrandt T, Dewenter I, Smolka W, Hesse E, Poxleitner P, Otto S.   +6 more
europepmc   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

British Journal of Pharmacology, Volume 183, Issue 18, Page 5476-5495, September 2026.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth, Malte Roessing, Moritz Lehners, Lisa Dietz, Anja Schmitt, Stephan Hailfinger, Andreas Peter, Leticia Quintanilla‐Martinez, Irene Gonzalez‐Menendez, Ingmar Mederacke, German Ott, Peter Sandner, Matthias Schwab, Robert Feil, Susanne Feil   +14 more
wiley   +1 more source

Multifaceted role of the vitamin B6 pathway in cancer: metabolism, immune interaction, and temporal and spatial regulation. [PDF]

Genes Dev
Mishra SK, Li B, Costa ASH, Van Aelst L, Zhang L.   +4 more
europepmc   +1 more source

Comparative Study of Laboratory Diets for Piophila casei: Beneficial Effects of Infant Formula Supplementation

Entomologia Experimentalis et Applicata, Volume 174, Issue 9, Page 1033-1041, September 2026.
The infant formula‐based diet (F), the whole powder milk diet (P), and dry‐cured ham (H) were evaluated for rearing Piophila casei. H accelerated development, promoted earlier reproduction, and achieved the highest demographic performance but showed practical limitations linked to substrate deterioration. F enhanced larval survival and adult longevity,
Diletta Missere, Maria Luisa Dindo, Antonio Martini, Alberto Lanzoni   +3 more
wiley   +1 more source

Complement Activation by Post‐Translationally Modified Proteins: Links to Chronic Inflammation and Autoimmunity

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
Marleen M. J. van Greevenbroek, Leendert A. Trouw   +1 more
wiley   +1 more source

Synergistic Effect Evaluation and Mechanism Investigation of Vitamin B6 and B12 in Models of Neuroinflammation. [PDF]

Int J Mol Sci
Dou X, Cai S, Liu Y, Wang J, Li H, Gao D.   +5 more
europepmc   +1 more source

Naringenin as a Multifunctional Ingredient Targeting Pathways Associated With Skin Inflammaging: Preclinical and Clinical Evidence

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Inflammaging, a sustained state of low‐level inflammatory activity with age, is a driving factor in age‐related changes in skin structure, function, and appearance. By perturbing fundamental biological pathways, inflammaging is a relevant target in skincare and anti‐aging research.
Taylor Oswald, Zixuan Shao, Nicholas Brideau   +2 more
wiley   +1 more source

Intake of Folate, Vitamin B6, and Vitamin B12 Before and After Disease Diagnosis and the Risk of Death in Individuals with Parkinson's Disease. [PDF]

Mov Disord
Zhang X, Flores-Torres MH, Christine CW, Bjornevik K, Hung AY, Schwarzschild MA, Ascherio A.   +6 more
europepmc   +1 more source

Omega Fatty Acids in Hair Loss Disorders: A Scoping Review of Preclinical and Clinical Evidence

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Omega fatty acids, including polyunsaturated omega‐3 and omega‐6 fatty acids (PUFAs) and monounsaturated omega‐9 fatty acids, regulate inflammation, cellular signaling, and tissue homeostasis, and may influence hair follicle biology and hair growth.
Nana‐Hawwa Abdul‐Rahman, Jacqueline D. Wang, Miriam Motlak, Gerardo Guiltarte, Reethi S. Padmanabhan, Ellen T. Lee, Sonal Choudhary   +6 more
wiley   +1 more source