Results 101 to 110 of about 431,419 (259)

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Manejo, prevención y control de la anemia perniciosa Management, prevention and control of pernicious anemia

Nutrición Hospitalaria, 2005
La anemia perniciosa es la causa más frecuente de anemia megaloblástica en nuestro medio y es consecuencia de una deficiencia de vitamina B12 debido a su vez a la disminución o ausencia de factor intrínseco (FI) por atrofia de la mucosa gástrica o por ...
R. De Paz, F. Hernández-Navarro
doaj  

Fluorescent Vitamin B₁₂–Platinum(II) Derivatives as Potential Metallotheranostic Agents for the Treatment and Imaging of Tumors

Inorganics
Vitamin B12 (cyanocobalamin) is an essential nutrient with very low bioavailability. Compared with normal cells, tumor cells show an increased demand for vitamin B12 to support their abnormal proliferation, which is a feature that can be exploited for ...
Rozan Mehder, Elena de la Torre-Rubio, Isabel de la Cueva-Alique, Ciaran O’Malley, Adrián Pérez-Redondo, Lourdes Gude, Eva Royo, Luca Ronconi   +7 more
doaj   +1 more source

Folate, vitamin B-12, and cognitive function in the Boston Puerto Rican Health Study. [PDF]

Am J Clin Nutr, 2021
Boumenna T, Scott TM, Lee JS, Palacios N, Tucker KL.   +4 more
europepmc   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Comparison Of Injection Vitamin B12 With Symptomatic Management in Clinically Suspected Vitamin B12 Deficient Patients: An Interventional Study

National Journal of Community Medicine, 2012
Objectives: This study was an attempt to evaluate the advantage of empirical use of Injection. Vitamin B 12 versus symptomatic management in clinically suspected Vitamin. B 12 deficient patients.
Janak Rathod, Taral Shah, Manisha Gupta, Rajendra Mehta   +3 more
doaj  

Maternal Mental Health in Late Pregnancy and Longitudinal Changes in Postpartum Serum Vitamin B-12, Homocysteine, and Milk B-12 Concentration Among Brazilian Women. [PDF]

Front Nutr, 2022
Batalha MA, Dos Reis Costa PN, Ferreira ALL, Freitas-Costa NC, Figueiredo ACC, Shahab-Ferdows S, Hampel D, Allen LH, Pérez-Escamilla R, Kac G.   +9 more
europepmc   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Vitamin B 12 and folate metabolism. [PDF]

BMJ, 1972
openaire   +5 more sources

Low vitamin B-12-high folate status in adolescents and pregnant women may have deleterious effects on health of the offspring. [PDF]

Am J Clin Nutr, 2021
Behere RV, Yajnik CS.
europepmc   +1 more source