Results 131 to 140 of about 450,034 (255)

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

The acute presentation of nitrous oxide-induced vitamin B-12 deficiency in a postoperative lumbar discectomy patient: illustrative case. [PDF]

J Neurosurg Case Lessons
Acharya A, Fossett D.
europepmc   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Examining the Clinical Usefulness of Urine Methylmalonic Acid for Diagnosis of Vitamin B-12 Deficiency in Older Adults: A Pilot Study. [PDF]

Clin Interv Aging
Bédard-Delisle C, Leonard G, Auray-Blais C, Reid I, Gamrani M, Chebbihi H, Presse N.   +6 more
europepmc   +1 more source

Optic neuropathy as a presenting feature of vitamin B-12 deficiency: A systematic review of literature and a case report. [PDF]

Ann Med Surg (Lond), 2020
Ata F, Bint I Bilal A, Javed S, Shabir Chaudhry H, Sharma R, Fatima Malik R, Choudry H, Bhaskaran Kartha A.   +7 more
europepmc   +1 more source

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

Are vitamin B-12 measurements adequate for evaluating its deficiency in individuals? [PDF]

Asia Pac J Clin Nutr
Özdemir S, Demirtaş S.
europepmc   +1 more source

Folate and Vitamin B-12 Status Is Associated With Bone Mineral Density and Hip Strength of Postmenopausal Chinese-Singaporean Women. [PDF]

JBMR Plus, 2020
Kalimeri M, Leek F, Wang NX, Koh HR, Roy NC, Cameron-Smith D, Kruger MC, Henry CJ, Totman JJ.   +8 more
europepmc   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Association between low vitamin B-12 status and latent tuberculosis infection among adults. [PDF]

Asia Pac J Clin Nutr
Jiang L, Yan T, Zhang X, Liu C, Yan Q, Chai Y, Li Y, Tan Y, Gao X, Wang Q.   +9 more
europepmc   +1 more source