Results 191 to 200 of about 863,295 (352)

Vitamin B-12 and neuropathy in the elderly [PDF]

The American Journal of Clinical Nutrition, 2016
openaire   +2 more sources

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease

Advanced Science, EarlyView.
CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee, Seunghwan Sim, Yinglan Jin, Hyejun Park, Eun Young Byeon, Su Jin Kim, Sujin Yun, Hye Eun Lee, Da Un Jeong, Jung Min Suh, In Hye Lee, Ho‐Young Lee, Yongseok Choi, Yun Soo Bae   +13 more
wiley   +1 more source

Serum Binding of Vitamin B₁₂ Analogues: Identification of Binding Groups in the B₁₂ Molecule* [PDF]

, 1963
L. M. Meyer, Peter Reizenstein, E. P. Cronkite, I.F. Miller, Claire Mulzac   +4 more
openalex   +1 more source

EETs Reduction Contributes to Granulosa Cell Senescence and Endometriosis‐Associated Infertility via the PI3K/AKT/mTOR Signaling Pathway

Advanced Science, EarlyView.
1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin, Weijia Gu, Xiaomei Tong, Mengru Lai, Yi Zhang, Na Liu, Xiaoying Jin, Chao Li, Dong Huang, Feng Zhou, Yongdong Dai, Songying Zhang   +11 more
wiley   +1 more source

Coprophagy and vitamin B₁₂in the rat [PDF]

, 1964
T. B. Morgan, Margaret E. Gregory, S. K. Kon, John W. Porter   +3 more
openalex   +1 more source

Monitoring the Dynamics of Alzheimer's Disease Biomarkers and the APOE–Tau Axis via Human Cerebral Organoids with Immuno‐SERS

Advanced Science, EarlyView.
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo, Youngjun Kim, Rian Kang, Seho Lee, Dang Du Nguyen, Soomin Park, Dongjoon Lee, Jong Won Han, Inhee Mook‐Jung, Luke P. Lee, Jong‐Chan Park, Inki Kim   +11 more
wiley   +1 more source

Vitamin-B₁₂Metabolism in Man Using Cobalt 58 (⁵⁸Co) as a Tracer [PDF]

, 1962
D. L. Mollin
openalex   +1 more source

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

Efficacy of folate and vitamin B₁₂ in lowering homocysteine concentrations in hemodialysis patients

Saudi Journal of Kidney Diseases and Transplantation, 2009
To evaluate the efficacy of supplementation with high dose folic acid with and with-out vitamin B 12 in lowering plasma total homocysteine (tHcy) concentrations in hemodialysis (HD) patients, we studied 36 HD patients randomized into four groups ...
Azadibakhsh Nassim, Hosseini Rahebeh, Atabak Shahnaz, Nateghiyan Navid, Golestan Banafsheh, Rad Anahita   +5 more
doaj  

MICROBIAL DEGRADATION OF CORRINOIDS I.VitaminB₁₂ [PDF]

, 1964
W. M. Scott, Roger Burgus, J. B. Hufham, J. J. Pfiffner   +3 more
openalex   +1 more source