Results 41 to 50 of about 916,090 (348)

Elevated Levels of Methylmalonate and Homocysteine in Parkinson's Disease, Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis [PDF]

, 2010
Background/Aims: Increasing evidence suggests that elevated levels of homocysteine (Hcy) and methylmalonate (MMA) may be involved in the pathogenesis of neurodegenerative diseases. Methods: The urine levels of MMA and serum levels of Hcy as well as folic
Bötzel, Kai, Giese, Armin, Levin, Johannes, Lorenzl, Stefan, Vogeser, Michael   +4 more
core   +1 more source

Validity and reproducibility of folate and vitamin B₁₂ intakes estimated from a self-administered diet history questionnaire in Japanese pregnant women

Nutrition Journal, 2012
Background No validated dietary questionnaire for assessing folate and vitamin B12 intakes during pregnancy is available in Japan. We evaluated the validity and reproducibility of intakes of folate and vitamin B12 estimated from a self-administered diet ...
Shiraishi Mie, Haruna Megumi, Matsuzaki Masayo, Murayama Ryoko, Sasaki Satoshi, Murashima Sachiyo   +5 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Solar ultraviolet-B radiation and vitamin D: a cross-sectional population-based study using data from the 2007 to 2009 Canadian Health Measures Survey [PDF]

, 2012
Background: Exposure to solar ultraviolet-B (UV-B) radiation is a major source of vitamin D3. Chemistry climate models project decreases in ground-level solar erythemal UV over the current century.
A Gozdzik, A Gozdzik, AE Millen, AF Bais, AR Webb, AR Webb, B Day, C Gagnon, D Rucker, DP Dee, E Giovannucci, E Liu, Ellie Farahani, EM Hume, FM Moy, H Sahota, Institute of Medicine, J Ahn, J Chan, J Wortsman, JA MacLaughlin, JA MacLaughlin, Jamie A Greenfield, Julia A Knight, K Langlois, LS Greene-Finestone, M Holick, M Tremblay, MF Holick, MF Holick, MI Hegglin, N Binkley, Norman A McFarlane, O Engelsen, Philip S Park, R Baraké, R Scragg, R Vieth, Reinhold Vieth, S Bryan, S Giroux, S Madronich, S Sloka, SJ Whiting, SR Cole, Suneil Malik, TC Chen, TG Shepherd, Theodore G Shepherd, TL Clemens, VE Fioletov   +50 more
core   +2 more sources

Vitamin B₁₂ in Foods, Food Supplements, and Medicines—A Review of Its Role and Properties with a Focus on Its Stability

Molecules, 2022
Vitamin B12, also known as the anti-pernicious anemia factor, is an essential micronutrient totally dependent on dietary sources that is commonly integrated with food supplements.
Žane Temova Rakuša, Robert Roškar, Neal Hickey, Silvano Geremia   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Characterization of hemodialysis membranes by inverse size exclusion chromatography [PDF]

, 1995
Inverse size exclusion chromatography (i-SEC) was used to characterize three different cellulosic hollow fiber hemodialysis membranes, i.e. low-flux cuprophan and hemophan and high-flux RC-HP400A.
Bargeman, Derk, Broek, Arnold P., Smolders, Cees A., Sprengers, Erik D., Strathmann, Heiner, Teunis, Herman A.   +5 more
core   +3 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

14C-Cobalamin Absorption from Endogenously Labeled Chicken Eggs Assessed in Humans Using Accelerator Mass Spectrometry. [PDF]

, 2019
Traditionally, the bioavailability of vitamin B-12 (B12) from in vivo labeled foods was determined by labeling the vitamin with radiocobalt (57Co, 58Co or 60Co).
Allen, Lindsay H, Buchholz, Bruce A, Calvert, Christopher C, Garrod, Marjorie G, Green, Ralph, Miller, Joshua W, Rossow, Heidi A   +6 more
core   +2 more sources

Decreased vitamin B 12 and folic acid concentrations in acne patients after isotretinoin therapy: A controlled study

Indian Journal of Dermatology, 2014
Background: Oral isotretinoin treatment might influence the levels of vitamin B 12 and folic acid. Aims and Objectives: The aim of this study is to compare vitamin B 12 and folic acid levels in patients with moderate and severe acne vulgaris with those ...
Hilal Gökalp, I Bulur, M A Gürer
doaj   +1 more source