Results 61 to 70 of about 79,292,901 (294)

Iodination of cisplatin adduct of Vitamin B-12 {B-12}-CN-{cis-PtCl(NH3)(2)}](+)

, 2007
The cisplatin adduct of vitamin B-12, {B-12}-CN-{cis-PtCl(NH3)(2)}](+) (1), reacts with iodide in aqueous solution to form {B-12}-CN-{trans-PtI2(NH3)}] (3) in good yield.
Mundwiler, Stefan, Medina-Molner, Alfredo, Alberto, Roger; https://orcid.org/, Ruiz-Sanchez, Pilar, Spingler, Bernhard; https://orcid.org/   +4 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Hampered Vitamin B12 Metabolism in Gaucher Disease?

Journal of Inborn Errors of Metabolism and Screening, 2017
Untreated vitamin B 12 deficiency manifests clinically with hematological abnormalities and combined degeneration of the spinal cord and polyneuropathy and biochemically with elevated homocysteine (Hcy) and methylmalonic acid (MMA).
Luciana Hannibal PhD, Marina Siebert PhD, Suélen Basgalupp MSc, Filippo Vario MD, PhD, Ute Spiekerkoetter MD, Henk J. Blom PhD   +5 more
doaj   +1 more source

Validity and reproducibility of folate and vitamin B₁₂ intakes estimated from a self-administered diet history questionnaire in Japanese pregnant women

Nutrition Journal, 2012
Background No validated dietary questionnaire for assessing folate and vitamin B12 intakes during pregnancy is available in Japan. We evaluated the validity and reproducibility of intakes of folate and vitamin B12 estimated from a self-administered diet ...
Shiraishi Mie, Haruna Megumi, Matsuzaki Masayo, Murayama Ryoko, Sasaki Satoshi, Murashima Sachiyo   +5 more
doaj   +1 more source

Vitamin B₁₂ deficiency and Parkinson’s disease

Неврология, нейропсихиатрия, психосоматика, 2023
Parkinson’s disease (PD) is a progressive neurodegenerative disease with various clinical manifestations, its origin not always can be explained only by dopamine deficiency. Long-term treatment with levodopa (especially its intraduodenal administration),
Z. A. Zalyalova, E. V. Ekusheva
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Obtaining Novel Vitamin B₁₂ Production Strains Acetobacter malorum HFD 3141 and Acetobacter orientalis HFD 3031 from Home-Fermented Sourdough

Applied Microbiology
Vitamin B12 is a critical nutrient in vegan and vegetarian lifestyles as plant-based vitamin sources are rare. Traditional fermented foods could be enriched by adding vitamin B12-producing bacteria to offer non-animal vitamin sources.
Lisa Stumpf, Stefan Schildbach, Aidan Coffey   +2 more
doaj   +1 more source

Plasma concentrations of vitamin B-12, 1-C metabolites and amino acids by vitamin B-12 concentration. Observations were stratified based upon the plasma vitamin B-12 levels more or less than 150 pmol/L (both visit1 and visit2 together).

, 2018
Plasma concentrations of vitamin B-12, 1-C metabolites and amino acids by vitamin B-12 concentration. Observations were stratified based upon the plasma vitamin B-12 levels more or less than 150 pmol/L (both visit1 and visit2 together).
Satish C. Kalhan (3492389), Chittaranjan S. Yajnik (451836), Carole D. Bennett (4349137), Prachi Katre (5278295), Lourdes L. Gruca (5278292), Dattatray S. Bhat (784878), Anura V. Kurpad (711381)   +6 more
core   +1 more source

Vitamin B-12 treatment of asymptomatic, deficient, elderly Chileans improves conductivity in myelinated peripheral nerves, but high serum folate impairs vitamin B-12 status response assessed by the combined indicator of vitamin B-12 status [PDF]

, 2016
Artículo de publicación ISISin acceso a texto completoBackground: It is uncertain whether vitamin B-12 supplementation can improve neurophysiologic function in asymptomatic elderly with low vitamin B-12 status or whether folate status affects responses ...
Ralph Green, Sánchez Reyes, Hugo, Castillo Carrasco, José, Green, Ralph, Fedosov, Sergey N., Hugo Sanchez, Miller, Joshua W., Jose M Matamala, Hertrampf, Eva, Jose L Castillo, Lindsay H Allen, Verdugo Latorre, Renato, Ricardo Uauy, Joshua W Miller, Matamala, José Manuel, Albala Brevis, Cecilia, Renato Verdugo, Brito, Alex, Setareh Shahab-Ferdows, Alex Brito, Verdugo, Renato, Cecilia Albala, Eva Hertrampf, Allen, Lindsay H., Sergey N Fedosov, Matamala Capponi, José, Uauy Dagach-Imbarack, Ricardo, Shahab Ferdows, Setareh   +27 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source